Endoscopic peroral jejunal fecal microbiota transplantation.

I am posting this to point out the potential dangers of oral FMT.

Any aspiration into the lungs is a real problem,just be careful what you do.
Old Mike

/www.ncbi.nlm.nih.gov/pubmed/27575658

BACKGROUND:

Fecal microbiota transplantation (FMT) is a valuable treatment modality for recurrent Clostridium difficile (C. difficile) colitis. Multiple questions including the best delivery route and volume remain unanswered. Here, we report a case series of high-volume FMT using endoscopic jejunal application route.

METHODS:

In prospective observational study, FMT was performed using fresh specimen from healthy unrelated donors to the patients with recurrent or refractory C. difficile colitis. Selection of the route was based on the patient's preferences. Specimens of at least 50g were dissolved in 500ml of electrolyte solution and administered using endoscope directly in jejunum.

RESULTS:

All procedures led to cure of C. difficile colitis. With exception of one case the procedure was well tolerated. In two cases, we observed FMT-reflux into the stomach despite deep jejunal application and in single case the FMT-reflux led to tracheal aspiration and severe pneumonia.

CONCLUSIONS:

High-volume FMT via endoscopic jejunal route is an effective treatment option that is well tolerated and easy to perform. Nevertheless, aspiration is potential life-threatening event that needs to be kept in mind during the FMT-procedure

I guess it's the same thing that normal fecal bacteria can cause infection of the bladder, different playgrounds for different bugs

Sharron: Was able to get the whole paper, looks like they did 6 people. I have been suggesting
that aspiration was a danger, ever since a guy on here did a poop shake.
There are also triple gel cap poop pills, people make, still does not protect from aspiration.

Old Mike
www.dldjournalonline.com/article/S1590-8658(16)30687-9/fulltext

Post Edited (Old Mike) : 10/26/2016 5:59:23 AM (GMT-6)

"However, I can totally understand these people, like the poop-shake man or the triple gel cap guy, who were so desperate that they acted more impulsively. I've been there myself so many times..."

That's the thing, if someone is going to try FMT then they ought to do it safely with a known process that's likely to set them up for success rather than only failure. Whether FMT works for everyone? Likely not but that's the case with viurtually every UC treatment out there, but certainly it will help some people as any treatment does. Do it but only the right way ...