Uceris Foam Increased Bleeding

I am new to the site but have had UC for the past 15 years or so. I was prescribed Uceris rectal foam due to a recent flair that got better with prednisone but my normal maintenance meds stopped working (canasa suppositories 1 x a day) and started Uceris rectal foam 2x a day for almost 3 weeks now and my bleeding just keeps getting worse. Has anyone else had this experience?

Interesting - my bleeding was exasperated with the first treatment with cortenema when first dx with proctitis … it was instantaneous and worsened with each subsequent application … after a few attempts I seeked another physicians care and was switched to rowasa (and Asacol) - worked like a charm and have been strictly on Asacol HD for many years now.

Thank you all for your responses! Little bit more back story… my UC is in my rectum only after showing some signs of possible crohns higher up about 10 years ago which was dismissed by my doc as a outlier. Been on sulfasalazine 2,000 mg per day and canasa 1000 mg a day for the past 3 years or so and everything was ok. I suck at taking my meds regularly and started to flair a year ago and have been on 2 rounds of prednisone which put me into remission only when I am on them but then flair back up shortly after and Canasa stopped working. Totally learned my lesson and take meds religiously now!

My urgency to go happens so frequently now, and when I do “go” (about 6 times a day) most times it is just mucus and blood.