It could be a fistula- if you didn't have the hole before, I'd guess that's what it is. But I've never had skin tags down there, so am not sure what they look like- don't they look like any old "regular" skin tag? Like a super long mole? If it's a fistula, rectal meds will not help heal it- the only meds they use to try to close those suckers are Remicade & immune suppressants. And I'm living proof that they don't work too well! If anything, my fistula has gotten bigger over the past few years, & I'm on tons of meds. Is the hole where they removed the skin tag? If they remove it like they do a wart, I guess you would have a hole.