I can't take Lialda or Asacol. I got really sick on both. My first symptom was itching, then a rash, then my neck hurt, the next day my wrists, then my knees, then I got such horrible pain in my stomach. It hurt so bad I was going to go to the ER. I thought I had toxic megacolon. I posted on here and heard this was a side effect. I also vomited. This all happened within a week of taking both meds. I stopped taking them and within a day or two I was fine. I hope you have better luck with Lialda. Alot of people use it and have good results. Good Luck!