Best time of day to take probiotics?

I just started taking Align last week, one pill per day. I also have started tapering off my 40mg of prednisone, and am having a rough time with it. I would like to double up on my Align in order to help myself get through this taper, but want to know what time of day is best to take the probiotics. Should I take 2 in the morning, 2 at night, or one in the morning and one at night? Does it even matter?

Thanks for humoring my over-analytical mind :)

I take Allign and the websites says....

It doesn't matter what time of day you take Align. We recommend that you take Align as part of your daily routine, at a time that will be easy to remember—such as when you take your usual vitamins or medications, or with your first cup of coffee.


Are there any special instructions for how to take Align?
No. You can take Align at any time of the day, with food or without. We recommend that you take Align as part of your daily routine, at a time of day that will be easy to remember—such as when you take your usual vitamins or medications, or with your first cup of coffee.

Flora website says....

When is the Best Time to Take Probiotics?
The best results are obtained if probiotics are taken regularly, preferably daily, to replace bacteria lost via aging and lifestyle and environmental factors. The latest research suggests that probiotics work best when consumed on a full stomach. Lactic bacteria are sensitive to extreme acidity and therefore, their passage through the stomach is easier when gastric juice has been neutralized by food.

I take mine after breakfast with my other medications.