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Prednisone- 1 time a day or 2 ??

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Posted 3/26/2010 1:39 AM (GMT 0)
Do you always take your whole dose in the morning or do you tend to split it

and take half in the morning and half in the afternoon?

Have you noticed any difference?

Thanks

Posted 3/26/2010 2:12 AM (GMT 0)
We were told once in the morning. I believe that's because of the sleep disruption issue. However, a GI friend of the family told me he likes to split the dose. We have had so many problems with pred and sleep that for us it's best to take it as far away from bedtime as possible.
Posted 3/26/2010 12:26 PM (GMT 0)
Unless you're on a pretty high dose, everything I've heard/read says take before 9am to keep your body clock in sync.   Higher doses do split, but is tough on sleeping!

I am on 40mg/day right now and interestingly, I find I usually get a spike of spastic energy between 5-6 pm....very unfocused, geared up prednisone energy.  Crawling out of my skin.

 

Posted 3/26/2010 1:27 PM (GMT 0)
I needed to split the dose because I wasn't doing well taking it all in the morning. I just metabolize it too fast. So I felt great for 12 hours and then like I wanted to die for next 12. If you are doing well, healing well, taking it all in the AM, then that's the best way to take it.
Posted 3/26/2010 3:25 PM (GMT 0)
I am on 40mg and have always split the dose-that is what I was told to do and I have never tried taking all of it at once. It does get me hyped up in the evenings, but I take a tylenol PM at bedtime and that is enough to lull me to sleep.
Posted 3/26/2010 3:35 PM (GMT 0)
I split my dose up a lot. Some people on here criticized my GI for prescribing it that way, but it seemed to work really well for me. I had no sleep disruption issues, either, but I don't think that has much to do with how I took it, and is instead b/c it doesn't bother me that way. Anyway, when I was on 40mg, I took 10mg at breakfast, lunch, dinner, and bedtime. When I dropped to 30, I dropped the bedtime dose, and so on and so forth.
Posted 3/26/2010 5:44 PM (GMT 0)
Usually it's prescribed once a day in the morning. That's because your adrenal glands would normally release your natural steroids at that time. Since their production is decreased or stopped when you're taking Pred, most docs like to simulate the natural cycle by having you take it in the morning.
Posted 3/26/2010 6:36 PM (GMT 0)
Judy-I did not know that! Very interesting. So I wonder if I should be taking it only in the morning? I don't intend to change up what they told me to do-but that is very interesting to know.
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