Favourite enema?

Hmmm well I don't LIKE any of them! :) But when I have to, I use the Hydrocortisone enemas because I am intolerant to all mesalamines. When I wasn't intolerant of them, I didn't have much trouble with the brand name enema Rowasa but I had issues with the generic because I couldn't squeeze the bottle all the way.

i am using salofalk foam enema and it works for me,, but my doc says if i aint bleeding not to use it,, but then i start bleeding again after a week or so,,,at the moment i,m trying to get a flare undercontrol and NOT miss my enemas,, as i am a sod for missing it, :( ,, no bleeding this morning yaaayyy , my fingers are crossed lol

Vitamin E enema.

To me this enema is the best treatment fo UC

Hi beckyinlondon

See link below

http://www.whale.to/a/ulc.html

Anthonyv said...
sorry to bring up an old thread guys but have many people tried vitamin E enemas?

I know several in these forums have including myself.

I have a generic Rowasa, 4g in 60ml. After about a month of dosing 3-4 nites a week, I think there has been some benefit. Still bleeding though, but maybe less.

I am thinking about adding some vitamine e oil (natural alpha-Tocopherol) to the bottle, about 10,000 IU in ~ 20ml food grade liquid.

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Luminal antioxidants enhance the effects of mesalamine in the treatment of chemically induced colitis in rats (http://www.ncbi.nlm.nih.gov/pubmed/18703751)

Author(s): Ancha HR (Ancha, Hanumantha R.)1,2, Kurella RR (Kurella, Ravi R.)1,2, McKimmey CC (McKimmey, Christine C.)1,2, Lightfoott S (Lightfoott, Stanley)3, Harty RF (Harty, Richard F.)1,2

Source: EXPERIMENTAL BIOLOGY AND MEDICINE Volume: 233 Issue: 10 Pages: 1301-1308 Published: OCT 2008

Abstract: Previous experiments in rats with chemically induced colitis have shown that the antioxidant N-acetylcysteine plus mesalamine (5-ASA) exerted a significantly greater therapeutic effect in promoting mucosal healing when compared to either agent alone. The aims of the present study were to compare the effects of three antioxidants plus mesalamine vs. 5-ASA alone in treatment of colitis induced by trinitrobenzene sulfonic acid (TNBS) in rats. Methods: Three days following induction of TNBS colitis, rats received 8 days of rectal therapy with 5-ASA, or 5-ASA plus vitamin C (ascorbic acid), 5-ASA plus phenyl butylnitrone (PBN) and 5-ASA plus vitamin E (alpha-tocopherol). Distal colonic tissues were examined for microscopic colitis and myeloperoxidase (MPO) activity. Results: Global assessments of microscopic colitis induced by TNBS indicated that 5-ASA alone significantly changed colonic injury by -31%. Combination therapy with ascorbic acid plus 5-ASA or a-tocopherol plus 5-ASA caused further significant change in TNBS colitis by -65 and -82%, respectively. Each of these values was significantly below scores observed with 5-ASA as monotherapy. Reduction in colitis with PBN plus 5-ASA was not different from 5-ASA alone. MPO activity was decreased significantly in response to monotherapy with 5-ASA and each of the antioxidants plus 5-ASA when compared to TNBS. alpha-Tocopherol plus 5-ASA, however, was the only treatment strategy that reduced significantly MPO activity below that recorded for 5-ASA alone. In conclusion, our results indicate that antioxidants other than N-acetylcysteine significantly enhance the therapeutic effectiveness of 5-ASA in the treatment of TNBS colitis. alpha-Tocopherol plus 5-ASA exerted profound anti-inflammatory and reparative effects upon colitis induced by TNBS.