Indersonu, I was also diagnosed with Osteopenia before I was 40 due to Prednisone use over the years. I've been on Fosomax since then (I'm almost 51 now). After a couple years they did another scan and told me the bones had regrown and I could go off but then I had a bad flare and put on prenisone IV's in the hospital. I then had to go back on the Fosomax after my next bone scan because I lost what I had gained. So I've been back on the Fosomax for 6 years but the good news is I haven't gotten any worse and haven't got full blown Osterperosis.