I also have a chronic fissure that was bothering me before I ever was diagnosed with UC. It heals a little and then comes roaring back whenever I get constipated or go too many times. It's agonizing to say the least, bleeds all the time and makes my life miserable. So my GI doctor sent me to a surgeon who says they don't like to perform surgery on fissures because too many patients become incontinent. He gave me a prescript
ion for a compounded ointment with 10% metronidazole. I'm using it now and at first it burned but there seems to be some improvement. All I can do is wait and hope that someday it will heal.