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My doc said it can't hurt to do probiotic enemas, started last night

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Ulcerative Colitis
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Posted 7/7/2010 5:52 PM (GMT 0)
My doc wrote As you know, the Bifiobacterium species live in the last four feet of the large colon as well as reside in the distal end of the small intestine; whereas the Lactobacillus live in the 26 plus feet of the small intestine. Bifobacterium will help reduce inflammation.   She's all for the enemas. I started with 4-5 capsules last night, you have to retain it to get the benefits. She said add a little salt to the water so you don't get dehydrated. I use spring water, not tap. I emptied a Rowasa bottle and used that last night and then again this morning. No improvement.   I will do it every night and morning for a week and see where I'm at. I want to see if I can go no meds until my scope on the 20th, so she can see the whole disease and how bad it may or may not be, I don't want to mask it by drugs right now.   I'll let you know how the enemas go.    
Posted 7/7/2010 6:51 PM (GMT 0)
I hope they help!! I am very interested in this whole idea. I have plenty of VSL3 (I get the DS by prescription), so I think I might try doing this.

Did you (or do you think it is necessary/helpful) use a regular fleet type enema first to clear things out so that the contents of this enema can get further up? And what do you use to wash out the bottle between uses?

Good luck!!
Posted 7/7/2010 7:47 PM (GMT 0)
I didn't do a fleet enema and I just rinse out the bottle because it doesn't let liquid go back into it when I insert it so it's clean. I just clean the tip with soap and water. I'm going to do it twice a day and stick with it.

My doctor sent me this:

 

Abstract

Ulcerative colitis (UC) is an acute and chronic inflammatory bowel disease of unknown aetiology, although bacterial species belonging to the normal colonic microbiota are known to be involved in its initiation and maintenance. Several organisms have been linked to the disease; however, mucosa-associated bacteria are more likely to be involved than their luminal counterparts, due to their close proximity to the host epithelium. Comparative bacteriological analyses were done on rectal biopsies to investigate differences in mucosal bacteria in patients with UC and healthy controls. Complex bacterial communities were found in both groups, with significant reductions in bifidobacterial numbers in UC, which suggested that they might have a protective role in the disease. Accordingly, a therapy for treating UC was designed, with the aim of modifying the mucosal microbiota to increase bifidobacterial colonization and reduce inflammation. Ranges of mucosal and faecal bifidobacteria were tested for their substrate preferences and their abilities to survive under a variety of environmental conditions. A synbiotic comprising a probiotic (Bifidobacterium longum) isolated from healthy rectal mucosa combined with a prebiotic (oligofructose-enriched inulin - Synergy 1) was developed. The treatment was used in a randomised controlled trial involving eighteen patients with active UC, for a period of 1 month. Rectal biopsies were collected at the beginning and end of the study. Bacteriological analysis and transcription levels of epithelium-related immune markers were assessed. Results demonstrated that short-term synbiotic treatment resulted in increased bifidobacterial colonisation of the rectal mucosa and induced significant reductions in the expression of molecules that control inflammation in active UC.

PMID: 15877898 [PubMed - indexed for MEDLINE]

 

 

Posted 7/7/2010 9:41 PM (GMT 0)
In a separate thread I decribe my experience of using VSL3 (which has plenty of Bifiobacterium bacteria) enema with good results. Hope you see some improvement soon. It is good to hear that there are GIs out there who keep up with research rather than pushing the same old stuff.
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