Sherry, I just looked and Depo is norethindrone which is a first generation progestin. If you're prone to acne, you do much better on something else. Ortho-TriCyclen was good for my skin, as is Mircette and Yaz (but I wouldn't recommend Yaz because it can cause other issues I've heard). Don't let her get a pill with levenorgestral either, those are pimple causing, high androgen pills. Those are brands like seasonale, levora, levlin, actually the majority of pills contain levenorgestral as it was one of the first progestins (look before you accept what they give you). I would give some type of Ortho a try or Kariva/Mircette, Desogen if you want higher estrogen but I don't see her needing that... Estro Step is supposed to be good for the skin but it broke me out AWFULLY. I would stay away from that one.
I remember being a teenager with skin problems and it's really horrible, I felt so insecure because of it. When I got to college, I used some AHA products that helped quite a bit (may be worth a try). I used Neostrata cleanser and it helped but it was short lived. When I finally started the pill, the change was incredible. I went from pimply to AMAZING skin. I felt so much better. I wish the dermatologists I went to offered the pill instead of all the topicals. The first pills I got was Ortho TriCyclen. The only negative to a triphasic over a monphasic is that you're not supposed to skip your period. I've done it with OrthoTri and never had any problems.
I am going to try desogen next or cerazette.
this is an interesting site:
http://community.livejournal.com/pillpamphlets