http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0000733/
Have you been on prednisone? Are you having potassium rich foods?
Before taking spironolactone, tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take. Be sure to mention ... prednisone.
Also: Talk with your doctor about the amount of potassium-rich foods (e.g., bananas, prunes, raisins, and orange juice) that you may have in your diet.