What causes the itching?

I finally got a script for Rowasa. With insurance it cost me $65. The pharmacist told me not to complain because without insurance it costs $1295. I unfortunately have to take the name brand and not the generic because of a sensitivity. I tried the generic last year and the next morning I had really bad leg cramps. Truthfully the GI and I are not even sure if that was the cause of the leg cramps but to be safe, he switched me to the name brand.

So I used my first enema last night and today I feel really itchy. The enemas definitely work because I had no blood today and the urgency is already gone. I felt itchy last time but I'm not sure if this is due to the Rowasa or from the proctitis itself. To clarify, its itchy on the inside, not just the outside of the rectum. I don't think its hemmies because that what I thought last year and the doctor told me I had no hemmies after I had my scope.

You mean even if its just rectal itching, this is a side effect? If so, is this a serious side effect or will it go away with a few days more of treatment?

If its an allergic reaction you're experiencing stop taking the meds. No offense but I wouldn't suggest masking the symptoms with something else like an anti-histamine unless you fully stop the enema until seeing your doctor.

Otherwise itching in that area is usually caused by tearing/inflammation/soreness from b. movements.

I took the enema last night and I have no more itching. I only had the itching yesterday morning after I had taken my first dose of Rowasa the night before. I have an appt at the GI doc today. I'll see what they say.