Probiotics - take with or without food?

take them according to what the bottle says. all probiotics are made differently so just trust the directions.

I use ProBio TX-11 made by Sangster health food store and the lady working there told me to take these particular ones on an empty stomach, so it really just depends on the instructions. I used to use Primadophilus Reuteri made by natures way and it guaranteed to target the colon, those were also instructed to be taken on an empty stomach.

I'm on Renew Life, Critical Colon and I read somewhere it's best to take at bedtime on a completely empty stomach. I never feel nauseous or anything from taking it, the tip I read (could have been here), was if you eat, the pill might get absorbed into your food and never make it to your lower colon. If you take w/o food and make sure your stomach is empty, it's encoated so it should go thru your system and then the capsule will open where you need it most. Sometimes I've wondered if I, prepare yourself, shove it up there like a suppository and not swallow it. Just kidding (but that thought has entered my mind!).