Rifaxamin in IBD metastudy

www.ncbi.nlm.nih.gov/pmc/articles/PMC3237300/

Sounds fairly well worth trying for anyone, like myself, that is having trouble getting and maintaining solid remissions. I am puzzled that it isnt tried more by GI's, since it doesnt sound very risky, as it's not a systemic antibiotic and nor is it very broad spectrum. Of note, a cohort of UC patients that did not suffer any relapses in several months, in one study, used a combination of the drug plus s. boulardi, the probiotic yeast, but I suspect that all sorts if good probiotics could be pulsed with it, including for e.g. mutaflor, VSL3 etc.

If most GI docs are like my doc, they have the mindset that UC is an autoimmune disease, so they won't consider the use of antibiotics to treat it.

Imagardener2- I looked up generic xifaxan on discount canadian online pharmacies and it seems rather cheap- less than $200 for a month's supply at the dosages for UC.

Have managed to stampout my latest (blueberry?) flare with a very modest surge if ored to 7.5 mg so I am not about to jump on xifaxan right away, but would like to stock it on hand if things get desperate. Hard to see how it could cause c.difficile but I suppose if used long term even a non shstemic could... i would not plan on using it long term though.; it would just be nice to see if it can break flares, sort of like jpouchers use antibiotics to knock out pouchitis, say.