Controls tight junctions in the small intestine,too much and you get celiac disease,wheat and others
cause the problem. Seems to act only in small intestine,but knockout mice get inflammed colons
from upregulated zonulin in the small intestine.
Here is some info read down. Just starting on this,see if it goes anywhere.
One thing to remember is if your small intestine is leaking then all kinds of stuff can
pass through.
Old Mike
http://physrev.physiology.org/content/91/1/151.long
http://gut.bmj.com/content/58/1/41.full.pdf+html
Seems I might want to make my sourdough with vsl3.
Regular old sourdough may also do it,makes me wonder before bakers yeast breads were naturally
fermented,the sourdough starter contains both bacteria and yeast.
http://thefooddoc.blogspot.com/2007/02/probiotic-vsl3-breaks-down-toxic.html
GOt to post these threads.
http://forums.phoenixrising.me/index.php?threads/a-gluten-protein-normally-is-too-big-in-order-to-pass-the-intestinal-barrier.5129/
http://www.celiac.com/gluten-free/topic/47795-zonulin-leaky-gut-and-gluten-sensitivity/
Oxalate,need to look at this more.
www.lowoxalate.info/papers/mechanisms.html
More.
http://blog.cholesterol-and-health.com/2011/04/what-no-one-is-saying-about-zonulin-is.html
Post Edited (Old Mike) : 11/28/2012 6:16:20 PM (GMT-7)