Remi-confusion

Hello! New here but looking for some opinions

Two years ago, my first flare was horrible and involved 30+ bloody trips to the toilet every day. Prednisone did absolutely nothing even in large amounts, so remicade 5 mg/kg happened. I essentially became normal overnight and was doing great for the next year.

I then started to have some intermittent mucous but could control it with canasa suppositories, and I still felt a huge difference the mornings after getting remicade. However, my last last two infusions haven't felt nearly the same, and for the past few weeks I've had pretty uncomfortable diarrhea and stomach cramping.

My GI ordered a Prometheus ATI test to determine if I had developed antibodies to remicade, but it came back negative. He thinks I simply need to be on it every 6 weeks rather than the usual 8. I'll have a stool test this week as well to look for any unwanted guests.

What do y'all think?

I think your GI is doing all the right things. I had a similar situation with Remicade but in my case even going to 6 weeks (and increasing the dose) didn't help me. I don't want to be negative but Remciade has a tendency to lose its effectiveness over time. Hopefully switching to 6 weeks will do the trick. Did your GI say if he was upping your dose too? Good luck.

Remicade started to lose effectiveness for me and we increased the dose and moved up the frequency. Unfortunately, it never regained it's effectiveness. Hopefully, it will work for you but you might want start checking out some of the alternatives...humira, simponi, etc.