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Question for those taking only 2 Lialda a day

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Ulcerative Colitis
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Posted 10/28/2013 6:35 PM (GMT 0)
My doctor told me he thinks I am well enough to drop from 4 down to 2 Lialda a day (first going to 3 and if I am doing well, drop to 2) at my last visit. So far I have been doing better since I dropped to 3 than I was with 4 and I am trying to decide if I should take 1 in the AM and 1 in the PM (which was how I took 4) or just take two at a time.
So for those of you who take only 2, do you split the dose? If not, do you take it in the morning or the evening?
I am sure none of this really matters but I am not sure where to drop my next pill, right now I take two in the morning and 1 at night.
Many thanks!
Posted 10/28/2013 6:38 PM (GMT 0)
I think you'll have to figure out what will be best for you. If you can take it once a day, that might be easier for you....

Please don't drop down to 2 after about a month of being only on 3.

Are you on rectal mesalamine as well?

q
Posted 10/28/2013 6:58 PM (GMT 0)
2 in the am... Dont think it matters.
Posted 10/28/2013 7:01 PM (GMT 0)
I am still on the hydrocortisone enemas while I sit for the sfrowasa to become available. None of the pharmacies in my area can get it right now.
I don't plan to drop to two any time soon, but I am a planner so I would like to get a sense of what others are doing as I develop my own plan.
Posted 10/28/2013 7:17 PM (GMT 0)
It sounds like a good plan...
q
Posted 10/28/2013 7:35 PM (GMT 0)
Recent sudies claim that there is no difference between taking it all one time per day (usually in the morning) or splitting the dose. I think most of the theory goes that patients are more compliant by taking it once per day instead of several times. Having said that, I noticed when I split the dose it works much better than taking it all at once. I take one pill three times per day. What are your current symptoms?
Posted 10/28/2013 7:38 PM (GMT 0)
I have taken 2 in the morning for 3 years now.
Posted 10/28/2013 9:35 PM (GMT 0)
I take 2 in the am also and any time I start to feel a little off I bump it back up to 2 twice a day. I've been doing well on this for over 2 years. :)
Posted 10/28/2013 9:42 PM (GMT 0)
Right now my only symptom is that I go twice a day more often than not. Pre-colitis I was only going once a day. Other than that I am pretty symptom free and it feels strange putting that is writing.
Posted 10/29/2013 1:04 AM (GMT 0)
I take 2 in the AM. I used to take 3 or 4 but since being on 6mp, I've been less dependent on Lialda.
Posted 10/29/2013 3:29 AM (GMT 0)
This is from a GI at Cedars-Sinai in LA:
You start out with the max dose of a medication, say 4 Lialda. You try to drop back to a lesser dose, 2 Lialda in this case. If the patient later starts to flare they now have the immediate option of increasing the number of pills without even calling the doctor. If you are already at a maximum dose then you are kind of stuck. That philosophy kind of makes sense to me.
I was told by another GI that splitting the pills over different times of day does not matter, but I do that when taking 3 or 4. It just feels right.
Posted 10/29/2013 11:58 AM (GMT 0)
naturalcurl, This is exactly what my doctor told me, although he says his patients tell him that four works best when split in two doses.
Thanks for all your input everyone.
Posted 10/29/2013 11:18 PM (GMT 0)
When I was taking 2 Lialda, I would just take them both at night right before sleeping. Now I'm taking four and I take all 4 at night after dinner. Since it works I don't really feel the need to experiment breaking the doses up.
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