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Are we more likely to get diabetes?

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Ulcerative Colitis
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Posted 5/5/2014 4:29 AM (GMT 0)
I don't have any family history, am a normal weight and don't eat very many carbs, eat clean foods most of the time, never drink soda, etc... I had gestational diabetes with my last pregnancy. I thought my levels would go back down after i had the baby, but they're still in the prediabetes range. Wondering if anyone knows of a link between mesalamine or autoimmune diseases and diabetes. My UC has been great, but now I'm so worried I'll end up with full blown diabetes. I was on prednisone 2 years ago for 2 months. Now I only take Canasa and 3-4 lialda pills.
Posted 5/5/2014 9:57 AM (GMT 0)
I thought it was something that came with steroid use, could be wrong
Posted 5/5/2014 12:58 PM (GMT 0)
Ulcerative Colitis is an autoimmune disorder and 25% of patients will get another autoimmune disorder. Type 1 Diabetes is an example of another autoimmune disorder. UC is an example of an immune system gone bad, attacking healthy tissue, and the immune system can find other such targets as well.

Long term usage of Prednisone can also induce diabetes.
Posted 5/5/2014 12:59 PM (GMT 0)
I've never heard of mesalamines being linked to Diabetes but prednisone sure has. People with autoimmune disorders are also more likely to come down with other autoimmune disorders.
Posted 5/5/2014 2:35 PM (GMT 0)
Steroid use is associated with developing Type 2 diabetes, which is not an autoimmune disorder. I would be very surprised if two months of steroids caused it though. Type 1 diabetes is an autoimmune disorder that you are a somewhat higher risk of developing due to your history of IBD. It's unusual to develop T1D as an adult but not entirely unheard of.

What does your doctor say?
Posted 5/5/2014 4:23 PM (GMT 0)
I'm taking my Post natal glucose tolerance as we speak so I'll see what my numbers are and go from there. I was just curious. I found this article talking about how fecal transplants could benefit diabetes patients as we'll and thought it was interesting.

http://www.bbc.com/future/story/20140429-medicines-dirtiest-secret
Posted 5/5/2014 7:04 PM (GMT 0)
Separate issue I would think, especially if one is on prednisone and/or has family related type 2 Diabetes.

Seems yours was isolated related to pregnancy....and you're being monitored...AND it's only 4 months after giving birth. It may take a while to get back to normal?

I've never read any issues with mesalamine-related diabetes...unless one might get pancreatic issues from the mesalamine. Again..separate issue and isolated subjectively.

Seems pregnancy would be a huge trigger for you, something to possibly not venture towards again.

q
Posted 5/5/2014 10:15 PM (GMT 0)
Many researchers start doubting UC is still an autoimmune disease...
Posted 5/6/2014 12:15 AM (GMT 0)
Thanks for your replies. I asked my OB through sobs for a referral so my husband could get a vasectomy. I have no desire to have another pregnancy with Gestational Diabetes. I had to go on insulin at the end so that's why I'm extra concerned. Just have to wait for my test results and go from there I suppose.
Posted 5/6/2014 12:16 AM (GMT 0)
Thanks for your replies. I asked my OB through sobs for a referral so my husband could get a vasectomy. I have no desire to have another pregnancy with Gestational Diabetes. I had to go on insulin at the end so that's why I'm extra concerned. Just have to wait for my test results and go from there I suppose.
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