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Oral capsule as effective as invasive procedures for delivery of fecal transplant

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Ulcerative Colitis
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Posted 10/11/2014 11:21 PM (GMT 0)
This is for c diff,but might guess will work for UC as a delivery method,if in fact really works well for UC,

which is still somewhat up in the air. Where to get acid resistant capsules. Have not looked.

Old Mike

http://medicalxpress.com/news/2014-10-diff-infection-oral-frozen-encapsulated.html

Posted 10/12/2014 12:11 AM (GMT 0)
maybe, but not nearly as much fun !

and no matter if was encased in a 3'' thick capsule, i'd still be putting poop in my mouth - uh uh - no way smhair
Posted 10/12/2014 1:27 AM (GMT 0)
http://www.bbc.com/news/magazine-27503660

Funny, I had just gotten done reading about that. They're being able to use synthetic now and not as disgusting and maybe more readily available.
Posted 10/12/2014 2:09 AM (GMT 0)
Oral FMT with pills was done over a year ago now. The only novelty here seems to be that they used frozen samples, which is important, but not mind blowing.

It may seem disgusting, but if its going to put me in remission, I can look past that
Posted 10/12/2014 2:31 AM (GMT 0)
http://thepowerofpoop.com/epatients/fecal-transplant-instructions/how-to-make-fecal-transplant-capsules/

http://www.ebay.com/itm/100-enteric-effect-acid-resistant-capsules-DRcaps-size-00-size00-EU-products-/280798967151
Posted 10/12/2014 2:39 AM (GMT 0)
Sign me up but I think in order to work for UC it will have to be tailored to the individual and probably an ongoing treatment plan, not a cure.
Posted 10/12/2014 2:45 AM (GMT 0)
you gotta read this smilewinkgrin

thepowerofpoop.com/fecal-transplant-success-story-1/

Somebody said...
My GI doc friend suggested a calprotectin test to evaluate the level of inflammation in my body. My score was 19- super low.

Post Edited (Dreadsteel) : 10/11/2014 8:48:49 PM (GMT-6)

Posted 10/12/2014 2:56 AM (GMT 0)
If I can acquire these types of pills, I may one day try them out. I recently learned about a "causal pie" model in epidemiology. journals.lww.com/epidem/Fulltext/2013/03000/Causal_Pie_Bingo_.22.aspx

I had infectious colitis a year before I was diagnosed. However, once that cleared up, I was totally fine until I took another course of antibiotics a 8 months or so later. I feel like having an infection on its own was not enough to cause autoimmunity in my colon, but it may have filled a piece of the pie, so to speak. I wonder if one could figure out all their environmental triggers, and could somehow reverse the ones that can be controlled, if that could induce and maintain disease remission...

I can think of a few environmental factors in my own case, and I think gut microbiome is one of them. I will definitely look into it more at some point in the future.
Posted 10/12/2014 11:31 AM (GMT 0)
It's possible that if you are actually allergic to something in the environment then getting allergy shots to that thing could theoretically bring on remission or maybe even possibly cure you. That's exactly what happened to me with my first autoimmune disease - I have been in remission for 15 years since getting allergy shots, which I continue to this day. Now with my other autoimmune disease and UC, it is a long shot, a very long shot - mostly because we don't really know that an allergy to something is actually the root cause and, in many cases, it probably isn't.
Posted 10/12/2014 3:16 PM (GMT 0)
@ Gary - What are these allergy shots youre taking? I dont have much background with allergies so Im curious
Posted 10/12/2014 4:59 PM (GMT 0)
Standard allergy shots. My first autoimmune disease, ITP, seemed to always act up, come out of remission, flare, or whatever you want to call it, every fall whenever I got a chronic sinus infection, which you could bet on happening every year. The sinus infection would last for months. Never believed I even had allergies because I did not have regular allergy symptoms like most people do, other than the yearly chronic sinus infection. It took me nine years to look into allergies and found out I had mild allergies to fall pollens and molds, just when my ITP would start acting up again. I tried several allergy meds and sinus sprays and even though they helped with the chronic fall sinus infections, they did nothing for my autoimmune disease. I decided to roll the dice getting allergy shots, knowing that it could make my ITP worse. The shots start out at extremely low doses and work there way up to desensitize the body to the allergens. After a few months of the shots suddenly my ITP went into complete remission and has been ever since. That was 15 years ago. I still continue the shots as an ongoing treatment as I have read that after stopping the shots altogether your allergies will often return again on down the road. For me, that was my trigger for ITP. Obviously it has nothing to do with my UC.
Posted 10/12/2014 5:23 PM (GMT 0)
Ah I see, so that shots contain a sample of the allergen then? Thats an interesting approach
Posted 10/12/2014 6:12 PM (GMT 0)
Yep
Posted 10/13/2014 8:11 PM (GMT 0)

Just in case you were wonder,frozen poop pills also work for c diff.

Driving me nuts though that they are using a blender,exposing the bacteria to oxygen and saline.

Old Mike

http://medicalxpress.com/news/2014-10-frozen-stool-pills-fecal-transplants.html

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