Gevokizumab

rbartolo

Regular Member

Joined : May 2011

Posts : 435

Posted 2/18/2015 3:12 AM (GMT 0)

One of my docs is suggesting I try Gevokizumab. anyone heard of it or tried it?

mcfarl73

Veteran Member

Joined : Sep 2013

Posts : 501

Posted 2/18/2015 3:16 AM (GMT 0)

Definitely thought you just made up a word right there lol

rbartolo

Regular Member

Joined : May 2011

Posts : 435

Posted 2/18/2015 3:18 AM (GMT 0)

Haha! Funny! I had to triple check the spelling.

mcfarl73

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Joined : Sep 2013

Posts : 501

Posted 2/18/2015 3:20 AM (GMT 0)

I've never heard of it, but I just Googled it and couldn't really find a ton about it. Is it a pill or an infusion?

Marauder93

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Joined : Feb 2014

Posts : 1185

Posted 2/18/2015 3:24 AM (GMT 0)

Well its an IL-1b antibody, so in theory it should work roughly like remicade/humira/simponi. But I havent ever heard of it before and highly doubt it is approved anywhere yet, let alone for IBD. Where did he hear about it?

DBwithUC

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Joined : Feb 2011

Posts : 4545

Posted 2/18/2015 3:45 AM (GMT 0)

It is not licensed. There are some trials for eye ulcers. Is he suggesting a UC trial? Do you know if it is a phase II or phase III trial.

Post Edited (DBwithUC) : 2/17/2015 10:27:08 PM (GMT-7)

xy123

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Joined : Feb 2014

Posts : 1137

Posted 2/18/2015 5:22 AM (GMT 0)

http://www.ncbi.nlm.nih.gov/pubmed/8292668
"Our results demonstrate that methotrexate blocks the interleukin 1 beta-interleukin 1 receptor pathway. Methotrexate is therefore another interleukin 1 inhibitor and a clinically efficient anticytokine."

Methotrexate is another IL-1 inhibitor.

rbartolo

Regular Member

Joined : May 2011

Posts : 435

Posted 2/18/2015 6:09 PM (GMT 0)

My Pyoderma came back & he thinks it will also help UC. Unsure if I'll continue to receive IVIG at this point.

DBwithUC

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Joined : Feb 2011

Posts : 4545

Posted 2/18/2015 7:00 PM (GMT 0)

It would be good if while treating the skin ulcers, the UC cleared up.

rbartolo

Regular Member

Joined : May 2011

Posts : 435

Posted 2/18/2015 11:29 PM (GMT 0)

IVIG was able to do that for a number of years. I always thought that as long as I had IVIG my PG would never come back. Sadly, I was wrong. I'm wondering if Entyvivo would help both UC & PG? No idea which drug is better. All I know is that there's a whole in my leg.

DBwithUC

Veteran Member

Joined : Feb 2011

Posts : 4545

Posted 2/19/2015 5:08 AM (GMT 0)

Entyevo was made to be colon specific in its action.

kiptyn

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Joined : Jul 2013

Posts : 608

Posted 2/19/2015 7:07 AM (GMT 0)

Worst. Name. Ever.

:)

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