High Eosinophils

How many are here that always or during the flare have high Eosinophil numbers?

Usually, this is concluded as inflammation marker by the GIs, at least mine does, but yesterday, I had an appointment with an allergist for my son, high Eos, plus sky high IgE (and food allergies). The allergist commented that my high Eos can not simply be concluded as inflammation, it can very well be high histamine/Mast cell activation related, esp. when there is any auto immunity component present.

I plan to follow up on this once, DS' things are sorted out, but until then I wanted to throw out a question to the community, if anyone looked into it.

Thanks in advance.

Ive had high eos count for years- at least 5! Its high when i feel bad and when i feel good. My gi says it is my allergies- i have chronic urticaria, tons of environmental allergies, nose bleeds, and food histamine intolerance.

delta, do you know what i'd look for in my bloodwork?? my gi and allergist have tested my igg levels a lot and have never said anything except that they are low.

Joanna,
For us the flag was high Eos and high IgA. That said it all, after physical exam (hypermobility, reflexes, nasal inflammation, none of which we knew before)

The test mentioned here has been ordered. https://www.healingwell.com/community/default.aspx?f=38&m=1838500 along with 24 hr urinary and plasma histamine. This (PGD2) is inflammatory in nature and acts along pathway involving mast cells.