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Has Salofalk supp. an irritation and diarrhea ?

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Posted 3/18/2016 3:07 PM (GMT 0)
Salofalk supp. or enema?

When I started to use the Salofalk enema 2gr 30ml, I didn't have any strange feeling and it worked very good for me and the bleeding was finished but I have Proctitis so my doctor picked Salofalk supp. 500mg instead of enema. The first time after using it, I have an irritation in my rectum and diarrhea, when I am using the enema I dont have diarrhea,constipation or bloat and my bleeding is finished.

Do you know why the supp. makes an irritation and diarrhea but the enema doesn't have these effects ?
What do you recommend to use in my situation, supp. or enema?
Posted 3/18/2016 5:34 PM (GMT 0)
Is it possible you have disease higher than the rectum which the enema was reaching, but the suppositories aren't?

Can't think of anything else, other than an allergic reaction to something in the suppository maybe.
Posted 3/18/2016 6:20 PM (GMT 0)
It's more likely you're flaring...bleeding isn't the only symptom to get rid of.

The liquid enemas have 60ml liquid, not 30 that I've ever used in the past. Is it a foam?

Ask to get back on the enemas and use the supps during the day.

ARe you on any oral mesalamine as well?

What were your initial symptoms when diagnosed?

q
Posted 3/18/2016 7:24 PM (GMT 0)

NiceCupOfTea said...
Is it possible you have disease higher than the rectum which the enema was reaching, but the suppositories aren't?

Can't think of anything else, other than an allergic reaction to something in the suppository maybe.

Doctor told me that I have ulcer at the end of my rectum and its size is 7 cm.
I don't know exactly but In composition of the Salofalk supp is written 2 gr alcohol but I don't remember that in composition of the Salofalk enema was alcohol or wasn't.
Posted 3/18/2016 7:34 PM (GMT 0)

quincy said...
It's more likely you're flaring...bleeding isn't the only symptom to get rid of.

The liquid enemas have 60ml liquid, not 30 that I've ever used in the past. Is it a foam?

Ask to get back on the enemas and use the supps during the day.

ARe you on any oral mesalamine as well?

What were your initial symptoms when diagnosed?

q

The enema was not like foam, it was written on that "rectal suspension Mesalazine Salofalk enema 2gr 30ml.
The doctor told the ulcer is at end of rectum, I think that's why he still hasn't gave tablets.

The ulcer size is 7 cm, The biopsy of colonoscopy shows that I have Proctitis from a mild(weakness) Ulcerative Colitis Symptom, after colonoscopy doctor told this is a mild colitis so picked Salofalk supp. 500mg for 3 weeks till next time when he will check my rectum. After using the supp. I had an irritation and diarrhea but no bleeding. In composition of the Salofalk supp is written 2 gr alcohol but I don't remember that in composition of the Salofalk enema was alcohol or wasn't.

How do you think, can the irritation and Salofalk supp. make my situation worse than before? I mean can it make the ulcer bigger or flare up the symptom?
Posted 3/18/2016 8:06 PM (GMT 0)
If after 3 weeks of Salofalk suppositories, things are no better, you need to either go back to the enemas or try something else - in fact most people take a mix of oral and rectal meds, but you seem to have a very cautious doc. Perhaps too cautious - it's not like mesalazine is a risky med. If he won't discuss medication matters with you, consider seeking a new doctor. It might seem a bit excessive, but you don't want to have a doctor who lays down the law and doesn't respect your wishes.

Incidentally, there is such a thing as mesalazine intolerance, which worsens UC symptoms, but if the enemas worked for you, then I don't think it can be that. Actually I missed something very obvious: the enemas simply have more mesalazine in them than the suppositories do: 2g as opposed to 500mg. They're stronger, that's probably why they work and the supps don't.
Posted 3/18/2016 8:49 PM (GMT 0)

NiceCupOfTea said...
If after 3 weeks of Salofalk suppositories, things are no better, you need to either go back to the enemas or try something else - in fact most people take a mix of oral and rectal meds, but you seem to have a very cautious doc. Perhaps too cautious - it's not like mesalazine is a risky med. If he won't discuss medication matters with you, consider seeking a new doctor. It might seem a bit excessive, but you don't want to have a doctor who lays down the law and doesn't respect your wishes.

Incidentally, there is such a thing as mesalazine intolerance, which worsens UC symptoms, but if the enemas worked for you, then I don't think it can be that. Actually I missed something very obvious: the enemas simply have more mesalazine in them than the suppositories do: 2g as opposed to 500mg. They're stronger, that's probably why they work and the supps don't.

In fact the enema which I used was before the diagnosis. After colonoscopy the GP(therapist) told me if your diagnosis shows that you have colitis you can use this enema but I started to use enema before biopsy's result till one week myself and it was very good, after my first using the bleeding was finished and I didn't have any problem more, when I went to check result of biopsy the specialist Dr. according to result of my colonoscopy decided to give me supp. for 3 weeks.

I read somewhere that Salofalk supp's irritation caused by Aminosalicylate which is in Salofalk supp. but I dont have any idea why Salofalk supp. makes this irritation but the enema which is stronger and bigger than supp. dosn't make any irritation for me.
I just can't understand difference between them.
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