Pentasa + Uceris

Hi all,
I've been going through this bad flare all summer that started in May after a C-Diff infection. After one course of antibiotics, a short course of Prednisone, one course of cort enemas, IV steroids, a bunch of Tylenol, IBS relief meds, and home remedies ranging from hot sugar tea to probiotics, I still haven't been put in remission. My new GI doctor suggested that Lialda isn't working on me anymore, and that we have to switch over to Pentasa or something stronger. I'm also being put on Uceris instead of going back on Prednisone.

Does anyone have any experience with Pentasa? Or maybe a combination of the two? How long till this is over?

do you know for sure the c-diff infection has been obliterated ?

Last time I had my stool checked was a while ago, in the hospital, a couple times. The testing showed the C-Diff had gone away. But I'll definitely bring that up, I believe I'm having a couple stool/blood tests coming up.

Most of the pain is in the lower abdomen. And it's not necessarily pain, it's more of a sudden urge to use the restroom followed by spasms and straining that lead to pain.

I am on Canasa.

I am a little confused as I thought that Lialda (mesalamine) was the same level of drug as Pentasa (also mesalamine) and so I can't see how you would benefit from changing over. It seems to me that you would need to go up to the next level of Drugs, something like Azathioprine. Also, I agree regarding the C diff, you need to be tested again as you may still have it.