Remicade levels low and antibodies present

Yes, that's great! I am really liking getting bloodwork weekly for Imuran (for a month; then it drops to once a month for 3 months) because it's really reassuring for me to see I'm ok and if Im improving. My bloodwork today was good. One thing went above normal range since taking the Imuran (MCV...a red blood cell value), but I looked it up and that appears to be a normal effect of taking Imuran and not normally a concern. And yeah, I felt completely normal all day today. I'm looking forward to my second Humira dose tomorrow.

Thank you, John! Did my second Humira shot today and it went well. Had the Humira ambassador on the phone and she talked me through it. Didn't have any medicine leak back out this time.

Hahaha! Thank you!

It sounds like you have a bit of health anxiety which pred is no doubt making worse. I would not assume osteoporosis at this moment, it could have totally unrelated and just been a freak accident kinda thing (I know I have the worst luck on stuff like that and am a natural born klutz). Right now, it sucks. You have a DEXA scheduled in less than a month and will find out whether there is any significant changes in density since your last (it could be unchanged).

While it is tempting to get off of the pred at a brisk pace, doing that prematurely will just return your UC to a flare. Best to give your new humira sufficient time to work, and then and only then begin a careful taper off of the dreaded pred.

I almost said, expect the next day's poop to be less formed (when I congratulated you the other day). But the good news is you saw the perfect poop, means you're healing, and you will start seeing better poops more and more regularly. Regular poops should become the normal over the coming weeks. Remember, play the long-game. Healing is never a linear path from flare to healed. Rather, healing is more akin to a rollercoaster ride, full of dramatic ups and downs, often we'll have a great day followed by a bad day (as frustrating as that is, it is normal and expected).

Certainly keep your gasteroenteroligist in-the-loop of anything else health related that occurs, but I would not expect a lot of concern over a fracture as another doctor (such as your general practitioner doctor) should be on top of that.

This is really bad constipation today. I can feel stool just sitting in my rectum but it won't come out. It's not tenesmus. Doesn't feel like that sensation at all. I'd much prefer explosive diarrhea right now. I really want to take a laxative. I'm going to stop taking my multivitamin with iron and see if that changes anything as I know iron can cause constipation (there is only 18 mg of iron in the multi. though and I've never had an issue taking it before but I also normally only take it on average once a week, not daily). It could also be the Zofran I've been taking, but again, I never had an issue with that in the past, although I've never taken it as often as I am now. I feel like I am constantly whining lately, sorry guys. lol.

Thank you, Flowers! Yes, I've been eating Metamucil wafers almost every day. I will get some apple juice and try that. I read calcium can also sometimes cause constipation, but I'm not going to stop taking that. I'll try to take less Zofran, too. I'm a little scared of stool softeners because when I first got UC, the first doctor I saw told me to take stool softeners and I did and then all hell broke loose! Before that point, my symptoms were a little blood and severe constipation. But maybe I'll try them if this continues. Thanks again. I missed my Rowasa enema last night (was exhausted and fell asleep), too. I may try to do 2 a day because the one day I had a perfect BM was a day after I had done a Rowasa during the day and held it in all day and night. That also could have just been a coincidence though! Lol. Hopefully the Humira kicks in for me and soon.

Sara, you mentioned earlier that you might take a laxative... Well this sentence you wrote: "I'm a little scared of stool softeners because when I first got UC, the first doctor I saw told me to take stool softeners and I did and then all hell broke loose! Before that point, my symptoms were a little blood and severe constipation" describes my situation exactly, I mean exactly!, except insert "laxative" for stool softener.

Hmm sounds like a muscle motility (movement) issue then. Why would our muscles not move as they should to evacuate stool?
1.) You say it's not inflammation as you can retain stool, remove that plausible cause.
2.) Second plausible is non-inflammation rectal wall thickening. If you had an xray, your rectal walls would appear thickened, it looks like a lead-pipe in xrays, so it's called lead-pipe. It can be from scar tissue formation. When our rectum walls are normally thin, the muscles within move in patterns of motion that move stool along. When the walls are thick, that results in either diarrhea (rapid, muscle spasms) or constipation (incomplete muscle motions).

You could try a fleet enema to move things along. You said the stool was right there but just wouldn't come out on its own.

https://radiopaedia.org/articles/lead-pipe-sign-colon

Well, a fleet will tell you with no uncertainty if you do have rectal inflammation. They're full of saline, salt water. The old expression "like adding salt to a wound." To this day, I always pour the salt water out and refill with tap water for flex-sigmoidoscopy preps. As I had a few fleets that hurt like all ungodly hell, and the scope revealed severe inflammation...

When that happened to me I used a steroid suppository instead of an enema for a couple days and things got back to normal.

Miserable feeling. Hope you get relief soon!

I just sent my doctor a message about it. I am having major anxiety. I am worried I am writing him too often and that he's going to get super annoyed with me. But I wanted to make sure I shouldn't be worried about this since it's been going on for weeks now! I wrote him 2 days ago also about my stress fracture.

The anxiety is likely from the pred. When I was on pred it seemed like I was always sending my doc messages and I felt the same as you -- that I was sending too many messages, but he and the nurses were great about it and said they like when patients use the portal.

~that is a crazy run on sentence but I'm not fixing it lol~

Did my 3rd injection today. Liquid came out again. Frustrating not knowing if I'm even getting enough of the medicine. It went perfectly last time when I was on the phone with the Humira rep. I think i picked a bad injection site because it hurt a tiny bit this time and it didn't hurt at all the other times. I must be squeezing my fat too much and squeezing the liquid out. I go down to 10 mg pred next week, so I guess I'll find out relatively soon if Humira is doing anything. My WBC went up from 8.6 to 9.9 this week. It had been steadily dropping from the Imuran. Not sure if it went up because I went down to 20 mg pred or if some fluctuation is normal or what.