Rowasa stopped working

I have been on Rowasa enemas for about two years to treat my mild/moderate proctitis. It worked like a dream until recently when I started noticing more mucus and some blood in my stool. It has progressively become worse since COVID. I am taking probiotics as well (Mutaflor). I had no symptoms prior and since I started taking it. My diet is largely Paleo. I was prescribed no other meds because this worked. Scope from a year ago showed no progression of the disease. I am now fearing that I will have to move up the med chain. I have an appointment with my GI Friday. Has anyone had this experience where the enemas started to fail? What might contribute to this. Was wondering if this is expected after prolonged use.

Thank you for the reply. I had been on Lialda but it did nothing after being on it for a few months. I also started getting headaches so was taken off.

Hi...ask for a steroid enema for a few weeks, or use steroid during thr day and Rowass for night.

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