Hi i had bad back pain with all the statins not to mention just a total feeling of tiredness. i have tried them all, Mevacor actually made me feel depressed, it wasn't until i gave up on them totally that i now feel better.I have to admit i am scared becasue my cholesteral is at 297 but i am going for quality of life not quantity. i am going to look up that Lipo matrix and see what is in it. never heard of it, is it canadian?