Hi BOO,I believe that 40mg Protonix twice a day is considered maximum. When I was on it, my PCP (and my asthma doc concurred) 300mg Ranitidine (Zantac) was added at bedtime, and for a time my asthma doc had me taking it in the morning as well.
It is quite common for GI docs to supplement the PPI with Zantac.
Good luck getting relief!
Denise