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right side pain from PPI's (nobody gets this?)

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Posted 7/22/2011 2:12 PM (GMT 0)
I had two in-hospital tests done and the first one showed the wide open LES. It is called an Esophageal Manometry test and the person administering it - two in my case - was standing there by me watching a computer screen image of my innards and calling out numbers to the other person standing on the other side of me.

The second test was a tube down my throat which they installed at the hospital and I wore it home for 24 hours and went back to have removed. It recorded acid and pressure etc or so I was told. Not too sure about anything but the acid part on the second one.

I only know I should have had them a very long time ago.

Good luck!
Posted 7/22/2011 3:17 PM (GMT 0)
Really? I hadn't heard of those side effects. I remember when I got this I saw "pancreatitis" as a side effect and freaked out. Now that I get it from taking any pills (even digestive enzymes, and I think chewable DGL (though the jury is still out), I think it must be intestinal irritation or that visceral hypersensitivity. If I had your symptoms and it was just from PPI's I'd definitely agree with your line of thinking, it makes sense.
Posted 8/2/2011 4:06 PM (GMT 0)
@ Hort, where did you see that muscle pain/twitching is caused by acid reducers? not doubting you, just curious.

I have had a relapse of the right side pain. I am only taking Align right now...I hate this. It is a strong pain, makes me very worried even though its been on and off for a year now. I wish I just knew what it was. Its been a year since I had an ultrasound on it (ultrasound was done when it hurt a lot, and it showed nothing). I don't think I can go years with this pain, its horrible.
Posted 8/2/2011 4:07 PM (GMT 0)
also, if I push in I really can feel that it is much easier to push in on the left side then the right. Makes me think the right side is swelled or something. Docs always say don't worry, buts its tough not to.
Posted 8/13/2011 6:02 AM (GMT 0)
hey sorry for the slow reply...i have been messing around with my meds for a bit now to see if i can get the pain to subside or go away...have switched from protonix back to the ranitidine and back and forth...everything seems to give me the same results...unless i completely quit them...lately i even am getting the side effect from tums...

here is the site where i was reading about muscle pain and the rest...

http://refluxdefense.com/heartburn_GERD_articles/side-effects-antacids-and-acid-blockers.html
Posted 11/21/2011 9:24 PM (GMT 0)
I had right side lower pain in my stomach with H2 Zantacs, not with PPIs.

First time i had GERD my GI put me on Zantach for 4 months, i developed right side pain after a few weeks, my GI didn't understand why and started talking it could be the appendix that is troubling.

Anyway it took years after i stopped Zantac before the pain went away and i went to ER many times during these years with no explanation.

I have GERD again now and tried Zantac and got the pain back at the first day, however i only took them for 3 days and then stopped due to other side effects and the pain thankfully went away slowly after 5 days or so...
Posted 11/21/2011 11:30 PM (GMT 0)

theacidrefluxman said...
@ Hort, where did you see that muscle pain/twitching is caused by acid reducers? not doubting you, just curious.

I have had a relapse of the right side pain. I am only taking Align right now...I hate this. It is a strong pain, makes me very worried even though its been on and off for a year now. I wish I just knew what it was. Its been a year since I had an ultrasound on it (ultrasound was done when it hurt a lot, and it showed nothing). I don't think I can go years with this pain, its horrible.

Yeah same here, they did ultrasound on me as well, showed nothing, also they did endoscopy, nothing, pain was really sharp like a knife and disapeared severals years after my Zantac medication, the pain was in such a bad area as well so you got worried it was inflammed Appendix all the time.
Posted 3/5/2012 5:47 PM (GMT 0)
I'm glad I have found this forum. I have been diagnosed with gastritis a few months ago (had an upper GI endoscopy). My symptoms are mainly intense nausea and bad taste in mouth, not really heartburn. My GP had put me on PPI (omeprazole) but that gave me really bad side effects (increased nausea!, back ache, total loss of apetite and slight abdominal discomfort). I was swapped to Ranitidine (Zantac 300 once a day before bed time). A week or so after starting Zantac, I started to develop pain in my right side, just below the ribcage. Sometimes, I also experience pain in the middle of my back. I though the pain might be due to liver, pancreas or gallbladder problems but I didn't experience it before taking Zantac.
I'm seeing my GP tomorrow and will report. I hope they will have an explanation and an alternative treatment if it is indeed drug side effects. At least I can tell them I have found people taking this drug that experience similar problem.
Posted 10/25/2012 6:33 PM (GMT 0)
Did any of you guys ever get an answer?

My symptoms are similar. I was diagnosed with gastritis 6 months ago after endoscopy. Pain is almost always on middle right side right under ribs, so both GI's I've been to are thinking gallbladder could be causing this issue rather than any gastritis in my stomach. Ultrasound and CT scan were negative, however. HIDA scan is next. GI doc says the gallbladder can produce pain in "squeezing" even if there are not visible gallstones on the scans.

I am intrigued by the idea that PPIs could cause gallbladder issues, as one study reports. I've been on high-dose PPIs for about 8 months, and before that about 4 years on OTC Prilosec. That would explain the location of my pain (URQ) as well as the fact that my "gastritis" is not getting any better despite a super-healthy diet, avoiding alcohol, coffee, spicy foods, etc., and large doses of PPIs and Mylanta. I don't know if it is the PPIs per se that cause gallbladder pain or simply the fact that your stomach is now producing very little acid, which makes the gallbladder try to overcompensate by squeezing out more bile...?

One of you in this thread mentioned golf: I notice it comes on a lot on the golf course. Movement seems to trigger something in there, and it's "inside" rather than muscular or bone.
Posted 11/12/2012 4:01 PM (GMT 0)
No answer for me yet...since my last post I've had a colonoscopy with nothing found...it's been over 3 years since I've had this pain with nothing to report...use a lot of salonpas patches on the area...my last doc thought nerve pain...who knows...yah I'm the golfer skeeve.

Acidfefluxman did you ever get any relief?

I'm not even on much for meds anymore as well...take about 1 a week if that...so I'm not sure this is even the right forum anymore! But it is worse the day after a pill of that matters.
Posted 11/12/2012 8:48 PM (GMT 0)
Hi Hort. My latest theory is a very basic one: gas. It is a known side effect of PPis because your stomach is not properly digesting foods. Gas can get trapped in the colon and cause spasms and pains, especially brief pains, which is what I have. The ascending colon makes a 90 degree turn on your right side under the ribs, so that is a possible hot spot for such problems. I've read that gas pains can mimic gallbladder attacks, and all my docs have been suspecting the gallbladder given where the pain arises. But tests have ruled that out.

With digestive enzymes and a low gas diet I am seeing if I can stop the problem entirely.... So far so good, but its only day one.
Posted 11/13/2012 6:25 AM (GMT 0)
I have the same right side pain. It comes and goes and seems to be worse when my heartburn is really bad. I've had ultrasounds, cat scan, hydra scan and they cant find anything. I have never thought that the PPI's were causing this nagging pain, but now I'm thinking twice about it. Sometimes I can go a few weeks with no pain and then it reappears with no change in diet, etc. I can't stop taking the PPI's so I guess I'll never know if it's the PPI's causing the pain.



Summer
Posted 2/21/2016 2:55 PM (GMT 0)
I hate to bump an old thread, but I'm rather desperate for answers. I too have had right side pain for over three years now. I have had a HIDA scan, ultrasounds, a colonoscopy, CT scans, MRI's, endoscopy and thus far no on can tell me why I have this pain. I quit drinking over two months ago to see if it would help, which was hard because having some evening alcohol always seemed to help with the pain. I've been on prilosec for years and was just prescribed protonix to take it's place because the last doctor who scoped me said "my stomach lining was a little too red". Really? Why would protonix help if I've been on prilosec already? Anyway, hoping maybe someone can update this thread if they ever found anything!
Posted 9/9/2016 12:25 AM (GMT 0)
I'm in the same boat. Center and right side pain (just under ribs). I've noticed that taking antacids immediately exacerbates the pain. I've tried every acid blocker there is. I took Prilosec for years without a problem, but this changed. I've noted that the more effective the antacid, the worse the pain.

I completely changed my diet, quit drinking and lost 50 pounds in the course of a year. I stopped taking everything but a probiotic, which seems to help. The pain is now dulled down, but still there. I recently started swimming and the pain came back pretty bad. I've had two endoscopies in 15 months, significant blood work, a cat scan, a hida scan and an ultrasound.

Results: I have a hiatal hernia, bile reflux and barretts. Also low white blood cell count consistently. The CAT scan came back normal.

Interestingly, with my diet change and quitting drinking, I never get acid indigestion anymore, but the right side pain persists.

The doctor has twice found significant bile in my stomach, which isn't good. Bile reflux I believe is the culprit. Treatment is very limited from my research, and the lack of knowledge in the medical field is troublesome. I told my 30+ year GI doctor that antacids cause my pain to worsen and he told me that was the first time he'd ever heard that.

I came across this paper (below), which is pretty wordy, but sheds some light, I believe on what's happening.

I don't know why the pain persists, but I think the lining of esophagus and stomach are compromised. Clearly, to some extent they are in my case as I have Barretts. Hope this paper helps someone.

http://www.surgery.usc.edu/foregut/demeesterpub/314.pdf
Posted 3/18/2017 11:45 AM (GMT 0)
Hi,

has anyone ever found out what's actually wrong? I would suspect it's the kidneys.

Did you try different PPIs and did anyone of them not give you the pain?

I also have the pain ever since I had pantoprozole for five days but I have it on both sides. Sometimes only left, sometimes only right.
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