Hi ARM,Have you ever tried Ranitidine in addition to PPIs? Before surgery, my PCP and asthma docs wanted me on 40mg Protonix before breakfast and before dinner, and 300mg Zantac/Ranitidine at bedtime. It seemed to help at night.
Have you read this article on how to get the most out of your PPI?
http://www.practicalgastro.com/pdf/January07/Jan07FrankArticle.pdf
Hope you had a better night last night!
Take care,
Denise