Feel like PPI is losing it's effect, need help!

CJ-Kenji

Regular Member

Joined : Dec 2014

Posts : 49

Posted 4/29/2017 4:54 PM (GMT 0)

I've been on prilosec 20mg for about 2 years now with good results but right now I constantly keep getting heartburn and I feel my stomach is irritable this has been going for 2 weeks now,, should I switch PPI medications at loss at what to do

law

Regular Member

Joined : Sep 2005

Posts : 93

Posted 4/29/2017 5:58 PM (GMT 0)

Hi CJ-Kenji,
It could be your body has gotten used to it. I was on Nexium 40mg for 10 years and it gave me stomach pain and heartburn by that point and so I went off. Most people would up their dose or switch brands if it isn't helping any longer. Did anything change with your diet? I used to have flares while on Nexium and then it would go but sometimes it took weeks (4-6 for me) for the flare to calm down. I had to be extra careful with my diet during that time as well. Then, it just stopped working no matter what I tried. Maybe try Nexium 20mg instead to make a change? I would not recommend upping your dose if you can.

CJ-Kenji

Regular Member

Joined : Dec 2014

Posts : 49

Posted 4/29/2017 6:20 PM (GMT 0)

Nothing really changed with my diet, but for the last week I switched to a high fiber diet since I have a bad case of indigestion and diarrhea at the moment, I feel like if I take a prilosec my heartburn and nausea will increase.

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