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A new drug for LPR, any feedback?

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GERD & Acid Reflux
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Posted 12/8/2021 7:03 PM (GMT 0)
Hi,

There is a new drug for LPR called Marial, which based on this article helps people who suffer from LPR:
https://www.intechopen.com/chapters/61811

Has any one tried it and if so, how effective is it?
Posted 12/9/2021 1:07 PM (GMT 0)
This is not a drug, it's a medical device only approved in some EU countries. I found some studies a couple of years old here in the US, nothing approved. I couldn't find any further studies after 2019.
Posted 12/9/2021 3:55 PM (GMT 0)
I think it is a medication:

From Dr. Thomas F. Lee, https://allaboutlpr.tumblr.com/

A NEW MEDICATION

Let me begin by telling you that this new medication does not appear to be available in the U.S. This blog is based on a publication by researchers at the Center of Regenerative Medicine in Genoa, Italy.

This medication is Marial, which they state “is effective in the treatment of gastroesophageal reflux disease and also of laryngopharyngeal reflux.” It is aimed at the body’s inflammatory response to reflux which they regard as a “potential protective event and not only harmful.” They refer specifically to mechanisms involved in tissue repair, which allows “ new therapeutic approaches.”

The scientists describe a new compound, named E-Gastryal that “has been proved to effectively relieve the discomfort caused by gastric reflux, preventing and alleviating the injury to mucous membranes. In fact, this compound is able to actively regenerate the damaged tissue…”

Combining E-Gastryal with magnesium alginate - a popular ingredient for relieving heartburn- results in Marial. It has been introduced into the market in Italy, and is made by Aurora, Milan, Italy. This is reminiscent of Gaviscon, the most concentrated form being available in Europe but not in the U.S.

Aragona SE, Mereghetti G, Ciprandi G. Gastric Reflux: The Therapeutic Role of Marial. Journal of Biological Regulators and Homeostatic Agents 2018, 32(4): 969-972.
Posted 12/9/2021 7:19 PM (GMT 0)
I did a search on Marial & what came up was a device under that name, you've done some searching & probably already know this. No where did a read that it's a medication. People that have blogs can write just about anything they want. I searched the archives here at HW & came up with nothing.
Posted 12/27/2021 3:33 PM (GMT 0)
Update:
I ordered Marial and got it about 10 days ago. You can order 20 oral sticks (15 ml) or 150 ml bottle with measuring cup. I went for oral sticks. I have used it since, and it has worked for me really well. My soar throat has improved, I would say, by about 80-90%. Marial can not be used for more than 30 days, but so far I have nothing to complain.

Post Edited (Johnny79) : 12/27/2021 12:04:23 PM (GMT-7)

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