Anyone get Depersonalization / Derealization / Disassociation with anxiety?

I have had brief episodes of what I think is depersonalization in the past but it never lasted. I'm currently on my 6th month if trying to find the right med/combo for a bout of anxiety/depression that started in February. I'd had bouts before but meds always worked right away. This time I was on a med that was pooping out and switched to another which wasn't a good switch.
Until around June, I'd "just" had most anxiety w/depression. Around June, I started getting those depersonalization/derealization symptoms of not feeling real. I described it as feeling like a stranger in my own familiar world and around loved ones. It's not 24/7 but enough during waking hours that it's bothersome.
2 weeks ago the Pristiq was bumped from 50 to 100mg. I was also put on 25mg Lamictal. For 10-11 days after med cysnges, felt so good and hopeful. A few days ago I started feeling that DP/DR low mood feeling again. Mostly in the morning but did have some at night.
Today I started increased Lamictal, 50mg.
Just wondering if anyone else has experienced this before. Success stories about it going away would be lovely too lol.
Thanks!
Lisa

Thanks for the reply Larry, most appreciated!
I've felt like it during a panic attack but it always subsides. This has kinda stuck around off & on for a couple of months. I've been trying to find the right meds to get outta the funk I've had since Feb. Might be my brain trying to cope with that stress.
Thanks again, it helps not to feel alone
Lisa
Ps: flourescent lights have always bothered me, yuck! I avoid places like Walmart at all costs. However, sometimes they're an inevitable necessity I read somewhere a gal wears sunglasses in Walmart for this very reason! Great idea

Thank you Merridia! It helps so much to know you're not alone as anxiety/depression is so isolating at times!!! Thanks for the good company
Lisa