Hi guys, I ran into a small Japanese trial (phase II) of a treatment that shows pretty amazing median OS data (73.9 vs 34.9 mo; p = 0.00084) in a selected patient group. Toxicity was very mild. The...
Ah, Katey - I am so sorry - I wish you all the best and hope that you will find the energy and faith to get through this! Thanks again and kind regards, m....
Dear Katey, I thank you very much for your post. I was very touched by your taking the time and sharing your experience. I am sure you have an awful lot on your mind, I can only begin to guess how...
Bad news for all of us who had hoped that PROSTVAC might offer an additional treatment option: The phase III trial of the vaccine did not demonstrate an improvement in overall survival compared with...
Thanks, Allen! In June of this year Bavarian Nordic said in a press release (http://www.bavarian-nordic.com/investor/news/news.aspx?news=5238) that they expect the PROSPECT study to read out final...
Thanks - that's better! m....
Yesterday Bavarian Nordic released this presentation at ESMO 2017 in Madrid, which includes information about the status of their phase III trial of PROSTVAC:...
JNF, Allen, Thank you very much for your recommendations! And oldbeek for the comment. Is there anyone who actually had a Provenge treatment in SoCal? best, m....
Hi guys, I am looking for a good medical practice in Southern California to get treated with Provenge / sipuleucel-t. I am looking for a good, friendly, efficient place with experienced doctors. I...
Redwing, Peter, Thanks for your input! Yes, a switch back to an agonist HT drug may well be an option. Initially I started my ADT with Zoladex (goserelin). First with the one month depot (which...
Friends, Two years ago I switched to Firmagon because of the very convincing mechanism and efficacy of the drug. The initial Testosterone suppression was excellent (2.5ng/dl). The only issue I kept...
Thanks, Simon, well, that answers my question. Bummer. I guess there might be exceptions but in general that combo does not look like a promising treatment option. Fairwind, Thanks for the post. I...
Hi Yarbo, You are asking about the lymph node dissection procedure. Here's my personal experience with that: I had a bit of a different diagnosis at the beginning, with lots of mets in bones and...
Dear friends, After a year with Enzalutamide (Xtandi) my PSA is coming back. It rose in two months from < 0.01 to 0.03 and now to 0.12. Still low, I know, but I am concerned about the growth rate. I...
snowcake, you might want to check out ISU-CycloneFan's posts. He has written in detail about his (positive) experience with Dr. Kwon. good luck - m....
Thanks, Allen & Bololidat, for the encouraging comments, and Jack for pragmatic recommendations! This all helps to keep a realistic perspective. m....
Jack, Thanks for your comment. Your making a good point and I totally agree with you, this is a different situation. I am just trying to figure out what I should do, and for that I am looking at all...
Hi guys, I am a high risk guy with GL 8, PSA 88.5, mets in bones and lymph nodes at diagnosis 2 years ago. After chemo, RP and while on ADT plus Enzalutamide my PSA dropped to < 0.01 for one year....
Allan, just got a 0.03 result from my psa test, up from < 0.01. as you can see in my profile i'm a 54 yr old high risk guy, after chemo, under adt and enzalutamide. latest scan (scintigraphy and ct)...
Thanks, Faustman, for your report. Please keep us posted! I am considering to get Provenge myself - but being from Europe I would need to pay the full treatment fee and I am honestly still a bit...
Dear brothers, I am looking for a good place to get treated with Provenge. I am a European patient and will have to travel to the States get this treatment as Provenge is not available over here. My...
Whow - Redwing, great news - I am so happy for you! Stories like yours give us all hope indeed, thanks for sharing! Guys like me with distant mets will probably need an even bigger miracle to get rid...
Todd, Great to hear about your love life :-) I must admit that I haven't had sex in a year. It's sad, but the ADT plus now the SE of the prostatectomy have taken that away from me, at least for now....
Dear Todd, This is a great opportunity to start with a big "thank you" for your blog, your willingness to share your experience and feelings. It has been important for me to read your story and I am...
Teamchris, One data point is no data point. I know it is hard to sit around and wait for the next PSA results to come in (I guess we all know how that feels...) but it might be the best you can do...
Sonny, I had 6 cycles of Docetaxel about one year ago. I never paid much attention to the amount of water I drank. The drug is in your system for about 24 hours, then it's gone. There is no need to...
Jerry Interesting to hear that you get Xtandi despite the fact that you are still hormone sensitive. All the best!...
Don - thanks for the additional info! And all the best for the chemo! I did six cycles of docetaxel and found it quite tolerable. it's not fun and the side effects get a little nastier with each...
Thanks, Don, for sharing your experience! What happened since Xtandi stopped working and how are you doing now? best, m....
Dear brothers, I need a bit of a morale booster. I am looking for Enzalutamide success stories. Is there anyone who has achieved a durable / long term remission with Enzalutamide? The official data...
Thanks, and yes, let's stay in touch! best, m....
Hi Ed Thank you for your detailed reply - that is very helpful! I need to look at that data regarding Celebrex, I was not aware of it. Yes, there is quite a discussion regarding the value of...
Hi Ed-Bar thanks for your post - very interesting - and congratulations regarding your PSA values and clear scans! Those are fantastic results. We seem to have a similar diagnosis (even the PSA at...
Hey Cyclone Fan - you just put a big smile onto my face :-) Thanks a lot for all your encouragement, your compassion and your excitement! I don't think that there is another member here who has more...
hi cyclone, thank you for your update - sounds like you are in excellent shape and in good (medical) hands! It is great to hear that your PSA has consistently stayed so low and I very much wish you...
Hi Cyclone Fan, Good to hear from you! I am glad that you are doing well - a consistent PSA of < 0.50 is great! I agree with you that more regular shots are a better option. I am having monthly shots...
Thanks, Fairwind, for your advice! I actually got the approval of my insurance company. I did another PSA test today and it shows that my PSA is rising (from a very low level of 0.05µg/l to 0.1µg/l -...
Hi Tall Allen, You have an excellent memory! A biopsy of a lymph node showed indeed some squamous cells. The picture however is - as often with cancer - not absolutely clear. The histology of the...
After initial diagnosis (metastatic PC) in Dec '14 I was treated with an ADT (Firmagon & Bicalutamide) plus six rounds of Docetaxel. This reduced my tumor burden significantly and PSA fell from...
Hi Beth, Thanks for your comment. You are right, this cocktail is not a standard treatment option for PCa. Here is why I am looking at it: So far my cancer has clearly been normal PCa. Now, a recent...
Who has been treated with a combo of Cabazitaxel plus Carboplatin? What was your experience? How well did the treatment work? I had six round of Docetaxel and might need to do Cab & Carb now. I found...
Dear all, I am in a weird situation and need your help: A year ago I was diagnosed with stage IV prostate cancer with mets in my bones and lymph nodes. After 1 year of ADT and six rounds of Docetaxel...
After 1 year of ADT and 6 months of Docetaxel I recently had a Choline F-18 PET/CT-Scan. The scan shows that my primary cancer as well as all of my mets have been significantly reduced. The choline...
Hi Sankalp, You were asking about my experience with docetaxel. It's no walk in the park, but absolutely tolerable. Let me first explain the procedure / schedule of the treatment. Taxotere chemo is...
Hi Sankalp, I would definitely get a second opinion. The ADT with Degarelix sounds fine. But I would very seriously consider doing chemo / Docetaxel, as Allen suggested. I am a stage IV, Gleason 8,...
Cyclone, That's a great thread you started! It's quite amazing to read these posts and hear about the lessons this illness teaches us. If it was not such a bitter drink it might be an excellent...
Yes, I know, classic catch 22... insurance does not pay, so there are very few cases, too few to prove that the treatment might actually make sense, and on that basis insurance companies don't pay...
There is a growing volume of literature discussing the benefits of aggressive treatment of metastatic PCa (for a good summary see: http://www.croh-online.com/article/S1040-8428(15)30038-X/fulltext)....
Teamchris, I had a similar diagnosis like your husband's. At the time of the diagnosis I did an MRI, a CT scan and a scintigraphy (bone scan) to determine the exact initial status of my disease. Then...
Hi Cyclone, I'm still trying to understand Dr. Kwon's recommendations. In general he is an advocate of an aggressive approach. So I am not sure I truly understand why he did not recommend surgery &...