I wonder if something like http://www.vitalstim.com might help with your upper sphincter....
Dr. Stephen Attwood, http://www.nugits.nhs.uk/nugits/surgeons/stephen-attwood/, is conducting a trial of Endostim. Endostim has been done successfully in one person in Chile who had a failed Nissen....
Why do think it's "internal" as opposed to actual motion? There may be motion but with a very low-amplitude, like a tuning fork. How fast is it, in number of times per second? Can you tell or is too...
The LES naturally relaxes for swallowing, gastric belching and vomiting. Not having it relax is a disease called achalasia. I don't think there is any qualitative difference between that relaxation...
Endostim definitely increases the baseline pressure of the LES, but somehow it doesn't appear to stop the natural relaxations of the sphincter during vomiting or gastric belching. One explanation may...
My understanding is that the LES is a circular band of muscle that is continuously being stimulated to contract. During swallowing, gastric belching, vomiting and sometimes spontaneously the...
This is essentially the way in which Endostim is presumed to work, automatically, in fact. How, if it is indeed the case, it does this is presently unknown....
To my knowledge, tLESRs are the primary mechanism of reflux in all reflux. Can you please share the research that suggested an alternative mechanism of reflux in LPR?...
I did some digging online and from what I found, prucalopride works only for constipation, at least all the trials being conducted for FDA approval are for that. However, the other drug referred to...
Are you not able to see any doctor you wish? Here are some expert reflux doctors in your country. http://www.manchesterrefluxconference.co.uk/speakers/...
Regarding your question about adjusting the device, I'm not sure, but I think many pacemakers, like heart pacemakers, come with that ability. My sense is that it doesn't need much tweaking after the...
The end dates for the studies are April 2013 and April 2014. I guess it wouldn't happen until the second study is finished, but asking the company would be best way to get an answer. I imagine by...
EndoStim is a company making an implantable pacemaker for the lower esophageal sphincter (LES). Reflux occurs when this sphincter inappropriately and spontaneously relaxes, the so-called tLESRs. From...
Hello Story, did you ever take the mirtazapine? If your condition was triggered by viral damage, due to the gastroenteritis you described, to your vagus nerve (the vagus controls the LES), I wonder...
Endostim trials... http://clinicaltrials.gov/ct2/show/NCT01578642 http://clinicaltrials.gov/ct2/show/NCT01574339...