AVN (avascular necrosis) is a complication that sometimes occurs from high-dose steroids. For reasons I don't quite understand, long term steroid use can cause the blood flow to your hips and/or shoulders to be severely limited. Without blood, the bones don't get nourished, and they slowly deteriorate. From what I understand, once it's visible on the x-ray, there isn't much you can do - you will eventually need some kind of surgery.
My mom had AVN in both of her hips a few years back, and ended up having to get a bilateral total hip replacement. It really was terrible watching her go from being fairly healthy to complete immobile in a little under a year. She had a fairly incompetent rheumatologist who gave her no medications except for 40mg methylprednisolone (equivalent to 50mg prednisone) for a year and accused her of trying to score drugs when she started complaining about
the hip pain. My mother has always been the type of person who'll tolerate extreme amounts of pain before saying anything. She got the point where she could barely move without crying. Her surgeon (who is a well reknowned surgeon, did one of the first hip resurfacings, and is a harvard medical school graduate) took a look at her x-ray and said something to the effect of "I really don't know how you even managed to move your legs with AVN this advanced; you should've had the surgery a long time ago". She's a lot better now and has retained most of her mobility - she can even sit on the floor (we had them put the absolute best hips possible; ceramic construction, large heads, etc..). Her disease is still fairly active, but she can at least walk again. My mom was 40 years old when all this went down btw.
Post Edited (terraphantm) : 11/27/2011 10:02:03 PM (GMT-7)