This looks very interesting. However, I wonder what the advantage of Orencia would be over any of the other TNF-inhibitors? It seems to be an infusion every 4 weeks! Remicade is every 6-12 weeks (8 weeks on average). So, you'd have to go in for an IV infusion fairly often. I guess, though, that if it works, and nothing else does, than it is a wonderful drug.