Hi Andrea. I was on Remicade for about 20 months. I LOVED it. It cleared up my psorisis wonderfully and my joints were doing terrific on it! Unfortunately, for me, I had to stop - I have a very weak immune system to start with and eventually started having allergic reactions to the infusions (mainly because my body couldn't handle it anymore, I think.) It was in my best interest to stop rather than continue with the infusions.
However, many people do NOT have this problem!
The infusion can take up to 3 hours to give, so bring a book and a water bottle. They often give Benedryl and Tylenol as a pre-med. Benedryl makes me sleepy, so wear comfy clothing to sit for 3 hours and in case you want to snooze!
I had immediate results. Because I was going through a severe bout of psorisis at the time, I saw it clearning up within 48 hours after my first infusion. The joints, after each initial infusion were showing signs of improvement as well. I was floored at how good I felt while taking the med - and supposedly it works even better if you take methotrexate while on it (I chose not to because I feel too rotten on it.)
Good luck. ***