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Posted 2/13/2013 6:06 AM (GMT 0)
I was just wondering if having a fast metabolisim would make your medication go through your system quicker. Like, would you need to take it more often than recomended?

 

I'm on Oxycontin, they say you only have to take it every 12 hours, but from the day I started on it, I had my pain back about 6 hours later. After being on it since 2001, I need to take it again every 5 hours

or I'm in pain & withdrawals are starting.

My new doctor asked if I wanted the old Oxycontin or the new one, called Targin, which supposedly has something to stop constipation in it, so I said I'd have the Targin. Then, I found that it had Naloxone in it, so it was made, not to stop constipation, but to stop people abusing it.

When I took it, swallowing it whole like you're supposed to, I went into withdrawals & it didn't stop my pain. My partner (who is also on Oxycontin) tried them also, but they worked fine for him. He is overweight, but eats healthy meals, where as I am quite skinny & eat jelly doughnuts only, for the whole day, or anything I can quickly through in the microwave. I can't stand too long to cook a propper meal beacuse of the pain. I'm having a hard time putting weight on because of my fast metabolisim.

When I told my new doctor that I wanted to go back on the old Oxycontin as the Targin caused me to go into withdrawals, he told me he was going to detox me. I couldn't work out why the Targin were blocking the receptors in my brain when they're are only supposed to reach the receptors in your gut, when they're used properly. Then, I suddenly thought that maybe with a fast metabolism, they are able to get to the brain receptors. Could anyone please tell me if this could be right ?   

Posted 2/13/2013 6:24 AM (GMT 0)
What medical testing have you had done to show that you have a faster metabolism than others in your age and weight range? If all you are eating are jelly donuts, and other fast prep foods, your diet may well be contributing to the problems you have with not being able to gain weight. Jelly donuts don't have enough calories in them unless you are eating massive quantities of them daily to sustain a normal adults daily dietary needs sufficiently.
Oxycontin is a long acting version of the medication oxycodone. The dosing schedule is supposed to be 12 hours, but some find that the medication doesn't seem to last as long. Targin is oxycodone and naloxone. Naloxone is used to prevent the misuse of the oxycodone if you attempt to undermine the time release mechanism. In other words, if you attempt to take it any other way than you are supposed to, whole, intact, pills, as directed by your doctor, the naloxone will be released instead, making the entire pill useless, both for the treatment of pain and any attempted diversion/misuse of the medication. It can throw you into withdrawal depending on how you attempt to divert the mechanism of delivery.
As to whether or not that has anything to do with you having to take the medication more often, I somehow doubt that your metabolism has much to do with that. Have you conferred with your doctor about changing your dosing schedule or did you make that adjustment on your own? Anytime that you feel that the medications aren't working to manage your chronic pain condition, you should always talk to your doctor and ask for his recommendations prior to taking any more of the medication than you are directed to take on the bottle. Doing anything else will get you dismissed from pain management and maybe permanently.
The old oxycontin is no longer available, since the new formulation was created to strengthen the anti diversion aspect of the medication.Naloxone only activates when you attempt to bypass the diversion mechanism in the medication, so a "fast metabolism" has no factor in this. What is the condition that you are being treated for?
What other modalities do you use to treat the pain, other than opiates? Therapies, injections, ice, heat , swimming, TENS, physical therapy?
Posted 2/13/2013 6:07 PM (GMT 0)
Htp you wrote back on January 30 asking questions about this medication. You need to talk to your dr about problems you are having that would be your best bet....Susie
Posted 2/14/2013 8:29 AM (GMT 0)
[img]/community/emoticons/nono.gif[/img] Why is it every time that I ask if anyone knows why I get withdrawals & my pain doesn't go, when I take Targin, I get a lecture. I keep telling you all that I took it the way it is meant to be taken & don't abuse it in any way, so I don't appreciate being told what happens when it's abused !! I'M NOT AN ADDICT!


I'm just trying to find out why this happens to some people & not others. I thought maybe it had something to do with metabolism & no, I've never been tested for this.



Also I know all about Naloxone & what it does so I don't need this explained to me over & over, thank you very much.



I got no real answer to my questions & I'm feeling quite hacked off.


Htp I had to edit one of your words out. This is a family oriented site and we have a rule concerning language.Susie

Post Edited By Moderator (straydog) : 2/14/2013 7:49:18 AM (GMT-7)

Posted 2/14/2013 9:19 AM (GMT 0)
I dont think anyones saying anything in particular since like Susie said when alot of us answer a post we go back to your older posts to get a clearer picture of your issues and refresh our memories.

When we go back to yours we see someone that comes asking about Targin and then gets put on it and displays the w/d symptoms that are only suppose to occur if the med is misused,we see 2 ppl taking each others meds,you stated that,asking your Dr to switch you back and forth several times in the course of weeks,and then the fact that your requiring it to be taken every 5 hours and its a 8-12 hr med.

The real clincher for me came when you also said you had to take restoril with every oxy or they did no good as its a sleeping pill and recommended for bedtime use not 5 times a day.

If you take a look at your own posts here honestly I think you will see a few flags that set some of us and most likely your DR too on the road to thinking somethings off here.

People come here for our opinions and that is what we give them based on what they tell us. We can only give you an opinion and not make a DX. We get some like yourself that doesnt like some of those opinions given,sorry but it is what it is and we dont mean to offend you.

Please just try to read your own posts from an outside looking in perspective and honestly you will see why we are having trouble helping you with the answers your hoping for.

We take what we want and need from the forums and everyones opinion and leave the rest.

Good luck to you and I hope you can get another Dr to manage your issues for you.

Vickie

Post Edited (nvrthesame98) : 2/14/2013 12:13:17 PM (GMT-7)

Posted 2/14/2013 9:31 AM (GMT 0)
Htp, you really need to have a talk to your doctors. As Vickie said, I don't think anyone is having a go at you.

Withdrawal when Targin is used normally is incredibly rare - I know that much. I experienced it when my PM switched me from OxyContin to Targin - and his response to me asking if it was possible was that he'd never heard of it happening but he "guessed it must be possible"...

By the by...Targin actually IS marketed as an opiate med to help reduce constipation - at least here in Aus. The way the Targin is formulated, the Naloxone is meant to act only on GI receptors (i.e., blocking the opiate effects in the GI tract). That's what my PM told me when starting me on it.
Posted 2/14/2013 10:55 AM (GMT 0)
Hi HTP! I remember reading something somewhere about Targin and w/d symptoms, but I can't find the articles right now. I will try to track them down. But from what I can recall, some people have experienced withdrawal symptoms while taking Targin and I think it has something to do with other medications taken at the same time. The naloxone, which is used to reduce the constipating effects of the oxycodone, breaks down differently when used in this capacity and can interact negatively with other opiates, sleeping medications, and others. I know this isn't much help, but I just wanted to let you know that you aren't going crazy (Lol! :-)) - other people have experienced the same thing while taking the medication correctly.

(Oops, I just noticed that CRPS told you basically the same thing!)

Post Edited (Splashdancer) : 2/14/2013 4:01:19 AM (GMT-7)

Posted 2/14/2013 2:54 PM (GMT 0)
Can you talk to your pharmacist & ask him/her this question? Other than as someone else suggested speak to your dr.

Susie
Posted 2/14/2013 4:47 PM (GMT 0)
IMHO there are 4 main reasons why your meds are lasting about 1/2 as long as being told they should.

In no particular order:

The medication is not "strong enough" and your pain is overpowering them quicker.

You are not really on a long acting pain medication and the doctor is only saying this to try to keep you on the absolute min. Not uncommon especially when first being put on pain meds or starting a new pain med.

As you suggested it is related to your metabolism or even your diet.

It is the wrong medication for you and is simply wearing off faster than average.

You really need to speak to your prescribing doctor about this. This really is the only person who can help you.
Posted 2/14/2013 9:17 PM (GMT 0)
Maybe the reason your Dr. said he was going to detox you is because you said the Targin is causing you to have withdrawl symptoms.

It's possible he assumes this means you're misusing it because the Naloxone is being activated.

You might want to further explain the situation. It could be a misunderstanding.

I don't have any advice other than that. With the way things are these days, even using the wrong word choices can send up red flags...and once that ball gets rolling it can be pretty hard to stop it.

We all have to be super careful about what we say and how we say it.
Posted 2/14/2013 9:26 PM (GMT 0)
I doubt the life span of your medication has anything to do with your metabolism. I have quite the high metabolism and my medication works as it is prescribed until my body builds up a tolerance to it.
Posted 2/16/2013 4:28 PM (GMT 0)
I mentioned this topic to my RN wife and she said that people can and do metabolize different things at various rates.
Posted 3/5/2013 4:31 PM (GMT 0)
Personally, threatening a doctor is not a good idea, unless I'm mus-understanding your post (which I may very well be doing) it sounds like you want to blackmail your doctor into continuing your medications? I realize that him giving you another patient's info is a HIPPA violation, but it was not done on purpose so I'm not sure what, if anything could be done to him. In my opinion, going on "current affair" will likely hurt you more than him.
Posted 3/5/2013 5:22 PM (GMT 0)
I'm having a lot of trouble reading your post - but if things go more smoothly with your partner there take your partner to each consult.

I too would advise against going to the media - at best it will antagonise your current dr - if by some slim chance the show takes up your story you will be remembered as a patient who ran crying to ACA - that's not to say I don't feel some sympathy with you if you've been using your meds correctly.

Also as far as OxyContin goes - the tablet coatings have always been indigestible and there has always been packet advice that this coating may appear in the stool... It is NOT the med itself coming out in the stool, only the empty casing
Posted 3/5/2013 10:03 PM (GMT 0)
Did I read this right? You went to your partner's doctor, who with no medical records whatsoever, asked you what meds you wanted and you told him so he wrote them out for you? rolleyes sad shocked

If that were me, I would have run out of that office as soon as he failed to want to see records or previous medical information. What kind of doctor does that? One that is not on the up and up does. That is truly frightening that you would consider that good or even adequate medical care.

As far as attempting to blackmail the doctor if he even dares to try to cut off your supply of meds, I wouldn't do that if I were you, in most states and countries, extortion is a crime and so is blackmail.

It was not my intent to insult you before in my previous response to your original post, and it is not my intent this time, but if I were your doctor, you would be dismissed simply for thinking that you could threaten me into giving you anything.

Good luck with your planned attempts, but I do believe it will backfire.

 

Posted 3/6/2013 8:57 AM (GMT 0)
Htp,

It looks like you deleted your post from earlier today.... but, after reading it, I felt compelled to just mention a couple of things.

As mrsm123 stated before me - it would be utterly irresponsible for a doctor to script you your meds (at those doses in particular) with no medical records, tests, etc. That is beyond scary.

All of us here know what it's like to have chronic pain.... and there are many here who have struggled or still are struggling to find the proper medication, doctor, etc. To me, it's critical that you find a proper, responsible PM doctor that will obtain your medical records.... and give you adequate, responsible care. We all deserve that. And, in return, it's up to us to be responsible patients....

Hope you figure your situation out.... but I would definitely find another doctor, or I think you'll find yourself in an even worse situation. --Tina
Posted 3/6/2013 5:26 PM (GMT 0)
I live in FL. As most of you probably know, we've had some pretty serious problems with pain management clinics and 'doctors' who prescribe controlled substances like they were Skittles. Luckily, some progress has been made and many of those clinics have been shut down. Anyway, through my many years of dealing with cp, there have been more than a few times when I've had to fight to get appropriate treatment - to find a good, reputable doctor. There have been stretches of time when I've had no pain medication and have had to face each day with pain at a solid 8, with spikes at a 9 - all because I couldn't find a reputable doctor who prescribed the medication I took AND took my insurance . It would have been very easy for me to go one county over, plop down a couple hundred bucks, and get basically anything I asked for. But to me, it just wasn't worth it. I don't want a doc who plays fast and loose with the prescription pad. And even though I am a legitimate cp patient, with reams of paperwork documenting my conditions, those places couldn't care less. They don't want to be bothered by the facts - they just want the money. I only want the minimal amount of medications to help control my symptoms, i.e. pain. But those 'pain management' clinics have the power to help turn a legitimate patient into an addict - and that is just so wrong.

I had a friend that I met at my CP support group, who went to one of those clinics. Her doctor had passed away suddenly, the office was closed and she couldn't reach anyone. The only place she could find that would take her right away was a popular 'pill mill'. Anyway, her usual prescription was for Percocet 5/325 - I think the quantity was 90. Well, she left the clinic with 2 prescriptions - one for 120 oxycodone 15mg AND one for 30 xanax! She had legitimate pain issues, was always careful with her medications, and took good care of herself and her family. Last I heard, she was in jail after wrecking her car while under the influence.

Post Edited (Splashdancer) : 3/6/2013 10:45:44 AM (GMT-7)

Posted 3/7/2013 6:18 AM (GMT 0)
Hey guys he posted in the anxiety forum,you might take a look at.

Interesting.

Vickie
Posted 3/7/2013 8:54 AM (GMT 0)
Um, yes - interesting......
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