WantRelief - I agree with PB4, you need to get rectal meds, I had the same symptoms and didn't get medical attention for it for quite sometime and it got progressively worse and then took longer to get better. I am using cortisone suppositories, I found them a bit easier to use then the mesalamine one and I had such bad inflamation I couldn't use the cortifoam. You do have to use the suppositories for a while before you see any improvement, and use them faithfully, don't skip doses. Good luck, I completely understand what a pain in the butt it is. Literally. - MB