I made the change from 6-mp to methotrexate injections about
6 months ago. The first few injections were really similar for me as they have been for you. My Rheumy upped my folic acid and that really helped with a lot of the symptoms. Make sure that they are doing bloodwork on your liver because both remicade and methotrexate can really effect it. I had to be taken off of both this past week due to elevated liver and pancreatic levels.