Vit B 12 problems

Hi everyone, I don't know if anyone can help me with some answers, but I've tried to research, but keep drawing blanks.

I've been having B 12 shots bi- weekly now for about 2 years. Now my specialist is telling me my values are still too low

Does any of you know why this is happening, and what can be done about it. I already suffer with neuropathy, I just don't
want to start getting into the more serious neurological problems. Thanks in advance.

Where is your inflammation? If it is where mine is, the terminal ileum, then that is were our bodies absorb all of their b vitamins. I too have chronically low b levels, and take a nasal spray, but am waiting on my most recent blood results to see if that has helped at all. I have not had any resections so even with all god's glory I am still unable to absorb the good stuff. See if your doc will give you a try on the nasal. Hope you feel better.

Mark Mac

Mark my disease is mostly in the ileum, and I also have pancreatitis so yes absorption is a major problem for me.

I haven't really worried too much about my B12 as I knew I was getting the shots, but when the specialist said he was
puzzled as to why there's no real increase, that's when I got concerned.

I was just interested as to why, when I am being supplemented, according to them with maximum dosing. Surely it should
be helping now, as it hasn't got to go through the gut...

They need to try you on a different form of injectable Vitamin B12. Hydroxocobolamine is easier for the body to use than cyanocobolamine. The body is supposed to convert cyano to hydroxo to methyl B12, but sometimes there is an error or deficiency somewhere in this process and the conversion doesn't happen so you just wind up losing the B12 without much benefit. Another possibility is that you're Vitamin B12 dependent. The Merck Manual says this is rare but possible, and requires daily B12 shots.

I like the methyl B12 because I don't get side-effects from it like I do from the cyano and hydroxo B12. Good luck,

Razzle & pb, thanks for the info. See this is what amazes me, you guys can come up with a reasonable explanation, but
my GI/ assistant professor and a specialist in the Crohns field is puzzled....

Surely I cant go marching into his office, spewing forth with this information...How does a lay person/patient handle this,
without stepping on toes.

You go girl....

I will try and take a leaf out of your book....

Okay...that wasn't an expletive I just used, I promise - just the acronym for Laughing My Butt (well, that was an expletive) Off. I guess I can't use that, oops.