The food is only a part of the equation. The larger part is the state of your gut. If permeability is high, all kinds of problems follow. If permeability is low, food does not matter so much. Following is a quote from a paper titled "Mucosal antibodies in inflammatory bowel disease are directed against intestinal bacteria."
We have previously shown that during
relapse of CD intestinal permeability is
increased3-5 allowing access of luminal constituents
to the mucosa. The acute inflammatory
response is, however, quantitatively an
order of magnitude greater than in other
conditions with similarly increased intestinal
permeability.5 This is probably caused by
increased intestinal immune responsiveness
caused by the underlying disease. The importance
of the interaction between luminal
antigens and the mucosal immune system as
the mechanism of relapse in inflammatory
bowel disease (IBD) is suggested by the following
findings.
(1) Known causes of relapse (intestinal
infections, non-steroidal anti-inflammatory
drugs, and stress) all increase permeability
across the epithelial cell layer or have the
potential to do so.5 6 Moreover, normal intestinal
permeability in patients with CD predicts
a long remission, whereas increased permeability
heralds relapse.4 7
It gets a bit technical after that, but you can see the importance of maintaining low gut permeability. Another paper - "Inflammation rather than nutritional depletion determines glutamine concentrations and intestinal permeability" states:
Results: The presence of inflammatory activity had significant negative effects on glutamine concentrations in contrast to the presence or absence of nutritional depletion. Similarly, intestinal permeability increased during active inflammation but not in depleted patients. FFMI but not inflammation was related to villus height.
So people who have inflammation have increased gut permeability - adding fuel to the fire in your gut. Getting the inflammation under control, keeping nutritional levels high and using a glutamine supplement all help to lower gut permeability. How to control inflammation is the tough question.
Post Edited (Keeper) : 9/2/2008 12:54:56 PM (GMT-6)