Ive been on Humira for about
3 months now. Sorry to say but the shots feel the same for me every time. They are pretty painful. The needle doesnt hurt me but the actual medication going into my skin does, its pretty thick. Just make sure you take it out of the fridge like 20-30 mins before you take it it helps a little bit with the pain. I also take some tylenol before the shot too, it doesnt help too too much but a little bit.