Hi Andrea,
I take my LDN each night around nine thirty before heading to bed. I normally go to bed around ten but watch TV and sometimes am still up for the eleven news. I had a lot more energy right off the bat. I do wake sometimes around three or four to pee, not sure if the endorphins taking off causes me to wake or not. I did have a few dreams the first week or so, nothing freaky though. I think I really sleep much better now. I've been on LDN since the beginning of November and have seen some definate improvements lately. Hope it works for you.
Take care,
Miss