Frustrated - Trial Drug failed :(

I opted for Cimzia most recently. Remicade was awesome for me, Humira was more than I could handle, and I'm hoping to the heavens that I have the nerve to do this Cimzia stuff. Biologics are scaring me too, but I'm desperate. And my doc and I also agreed that Tsyabri was scary and that we'd both vote for Cimzia first. I don't know... I'm sorry you're going through this too. It sucks to have to decide which is the lesser of the "evils".

I too have thought about stepping "backwards" to the pills, but I really didn't respond well to any of them when I tried 5 years ago... I just wasn't in any shape to experiment before they jumped to the Remicade, so I'm wondering if maybe I COULD get away with maintenance meds like Imuran once I get my intestines somewhat healed up...

I wish I had something more "uppity" to say... just want you to know you're not alone! I hope you start to feel better soon and that your "lupus" and joint pain disappear with the remnants of whatever it is that's making you so miserable.

I know how frustrating and disappointed you feel when yet another med doesn't work. I must have tried them all, too, including 5 trial meds. Ironically, the one that helped me the most was Tysabri, when it was still in trials. But I'm also afraid to take it now that it's approved.

I had to take Remicade for my scleritis of the eye to get the eye under control. After 10 infusions 4 weeks apart I reacted so rather than jump right into Humira, I stepped back to Immuran. That was last September. So far so good.
Dave D

Thanks, I'm probably going to give Imuran a shot and if it works it works, but if it fails, onto surgery...