Also, I forgot to add. Have you tried Remicade? If not, I think you should. It changed my life. I didn't like Pentasa, it didnt' help, it made me go to the bathroom more. If you need Remicade info ask your GI specialist or ask me. I also submitted a post with the Remi Start program for Remicade Assistance. Hang in there, I know it's tough I have been battling this for 28 plus years and finally about
3 years ago I found a GI Specialist that got me on Remicade Infusions. I have had no issues since.