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Humira question
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Crohn's Disease
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dmc24
Regular Member
Joined : Aug 2007
Posts : 37
Posted 10/19/2009 5:06 PM (GMT 0)
Does anyone know why the first time I take humira, i have to have 4 shots.
Also does anyone take Pentasa with Humira?
Former58D
Regular Member
Joined : May 2009
Posts : 173
Posted 10/19/2009 5:45 PM (GMT 0)
While I don't take Humira at this point (that might change tomorrow when I see my doc), the reason you load up with 4 shots is for the induction phase, or to induce remission. The standard protocol would then have you transition to one shot (40mg) every other week for most folks. Some take a shot every week. Your doc should be able to explain it to you.
dmc24
Regular Member
Joined : Aug 2007
Posts : 37
Posted 10/19/2009 5:53 PM (GMT 0)
Thanks so much for your response.
How do you like 6MP? I didn't like it that much.
Former58D
Regular Member
Joined : May 2009
Posts : 173
Posted 10/19/2009 6:07 PM (GMT 0)
Funny you should ask. I've been on it 4 months and I decided to stop taking it last night. I see my doc tomorrow to tell him the good news. I never had any tangible side effects like hair loss or elevated liver enzymes. My WBC went down initially and then it went back up - weird. Basically, for the past 6-8 weeks I've felt slightly nauseous, slight, but persistent abdominal discomfort, and general malaise. My issues are all in the rectum and my stomach never hurts, but this was going on 24/7. I also got diarrhea, which I think is unrelated to the Crohn's. I didn't have run to the bathroom D, my BMs just got softer and softer. I totally chalk it up to the 6MP.
I expect tomorrow we'll discuss remicade and humira.
NostraHistoria
Regular Member
Joined : Nov 2008
Posts : 348
Posted 10/19/2009 9:19 PM (GMT 0)
I am starting Humira soon, too. They are going to give me 4 shots in my abs. :( I am scared. I heard you can take it in your leg.
potatoqwn
Regular Member
Joined : Jan 2006
Posts : 355
Posted 10/20/2009 5:23 AM (GMT 0)
Nostra don't be scared. The stomach shots are much better for some reason. Not as painful. Don't know why. Listen, we have all been dealing with Crohn's. Some little shots are really nothing compared to all that we have endured. Besides, the shots hurt only while you are getting them. The pain subsides almost immediately. You'll see. Good luck. Hope it works for everyone.
dmc24
Regular Member
Joined : Aug 2007
Posts : 37
Posted 10/20/2009 12:27 PM (GMT 0)
potato, do you take the shots? Any side effects?
tamsprote96
Regular Member
Joined : Apr 2009
Posts : 55
Posted 10/20/2009 2:56 PM (GMT 0)
I'm on Humira and Pentasa. I haven't seen any bad side effects from either. I take the Humira in my leg. It hurts but only for a minute then it goes away. I figure a minute of pain is worth the remission.
dmc24
Regular Member
Joined : Aug 2007
Posts : 37
Posted 10/20/2009 2:56 PM (GMT 0)
Thanks, this is good information.
Iram
Regular Member
Joined : Jul 2003
Posts : 145
Posted 10/20/2009 3:10 PM (GMT 0)
I am on remi, prednisone and pentasa. so far I have had only one infusion.
potatoqwn
Regular Member
Joined : Jan 2006
Posts : 355
Posted 10/21/2009 12:57 AM (GMT 0)
dm,
I used to take Humira and had wonderful results for 3 years. But sadly I developed the antibodies to it. Darn. It was a great 3 years though.
No serious side effects at all. Just some minor redness, itching and swelling at the injection site. I did take Benadryl one hour before the Humira per my doctor.
ISF13+
Regular Member
Joined : Jun 2009
Posts : 202
Posted 10/21/2009 2:51 PM (GMT 0)
My doc refers to it as the uptake dosage. In other words, you get alot of the drug on board so that you don't bottom out before your next dose. After that, you should have a steady amount of the drug in you. It really sucks though doesn't it? I don't know about you but those shots hurt a LOT. I recently switched over to the injectable version and I'm not sure its any better because it goes in so S L O W L Y. It's a no win with me I'm afraid. I just brace myself and let my husband do the jabbing. Good luck. I hope it works out well for you. I've been on it for about 2-yrs now.
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