He is using a cortisol (entocort) to downregulate the proinflammatory proteins (which is likely the bacteria problems in the first place or the fact the inflammation has led to further leaky gut) which has led more inflammation to occur. The benefit of antiinflammatory from the cortisol also has the affect of altering the glucose metabolism (cortisol is opposite of insulin).
You can act by simply avoid the proinflammatory proteins in the first place by avoiding wheat protein and gluten, bacteria, yeast etc..
The imuran will further depress the insulin by affecting the imidazole part. The imuran also breaks down to mercaptopurine which will then lower your immune system as well as your glycoprotein synthesis.
So given the magnitude of these metabolic areas a small pain reliever seems to be a very small request. Thus the areas affected by these meds is overwhelmingly extensive for just reducing inflammation. Nevertheless this is the treatment that is used to reduce inflammation when inflammation is extreme.
The uptake of glycoproteins (or allergens) is influenced by glucose (and also dependent of the terminating sugar part of the carb-protein chain). so if a glycoprotein is encountered in the bowel the more glucose you have the less uptake [emphasis added] of the glycoprotein. On the other hand if the imuran is targetting the mucous from within then this is after the fact of having consumed a glycoprotein or having encountered a similar looking allergen.
*Medchrt, could you please respond to folks in laymens terms instead of these medical book like responses. Remember we are just regular folks living with this darn disease. Thanks for your understanding.
Post Edited By Moderator (Nanners) : 1/31/2010 7:47:51 AM (GMT-7)