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Saccharomyces Cerevisiae in Crohn's???

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Crohn's Disease
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Posted 3/13/2010 12:03 AM (GMT 0)
   Does anyone have any idea what these levels have in relations to Crohns? It seems that they are yeast antibodies, the two most prominent ones being Saccharomyces Cerevisiae IgG and IgA. Also he tested for Atypical pANCA, but it seems it came back negative.
   This is how my doc helped in diagnosing me. With a blood test looking for these. Apparently mine were really high which strongly points to Crohns, but also may indicate other issues.
   Just wondering if anyone has any ideas. I'm gonna do some research.
Posted 3/13/2010 12:34 AM (GMT 0)
No, but it's intriging...maybe you could throw your question about the yeast antibodies out on the Celiac board. They probably could give you some good info...please follow up here though for all the stubborn ones such as myself that aren't quite gluten free yet.
Posted 3/13/2010 12:50 AM (GMT 0)
What were your results ? Was your asca IgG or IgA positive, or both? My IgG is positive I think at 120. From what I have read they use this more in the pediatric population. Some docs put more faith in this test than others. My colon biopsies have not shown crohn's, just regular inflammation. After a year of colazal, my biopsies were negative. I have heard this test can be positive in people with celiac. I have tried a gluten free diet without any results. So, that's my asca story. This year, after I got my primary care doc to do the asca test and it was positive, my GI did an enterography to get a pic of my small bowel. It did not show any inflammation, so I guess they feel I don't have crohn's. Well, that along with the negative biopsy. I guess I'll wait and see, keep taking my meds and watching the diet. I hate ti jinx myself, but right now, I am doing ok
Posted 3/13/2010 1:09 AM (GMT 0)
TO jeanneac - both my IgG and IgA were above normal (positive). But what I'm trying to research is what do (baker's yeast) antibodies have to do with Crohn's? Maybe its from years of bad diet or something. Who knows. Its interesting to me now.
Posted 3/13/2010 1:14 AM (GMT 0)
idboer, the fact of the matter is that at this point, not even IBD researchers know why yeast antibodies are frequently elevated in Crohn's patients.

So, to answer your rhetorical question of "who knows?", the answer is "nobody." :-)
Posted 3/13/2010 1:27 AM (GMT 0)
Yes, I was wondering that too, why an antibody to yeast??? I thought perhaps I should avoid all foods made with bakers yeast such as breads. so, did your doctor feel that since both antibodies were positive that you had crohn's? Have you been scoped and had biopsies at all?? I was curious as to the results. I have read some articles on medscape about the asca antibodies. It seems they are also positive in another auto immune disease called Bechet's disease. Apparently, the test has been out for quite some time, I just wish they knew more about it or would do more research on it.
Posted 3/13/2010 3:29 AM (GMT 0)
I dont know much about yeast but doesnt it have to do with the bacteria in the bowel? Like when antibiotics kill all your good bacteria in the bowel you can get thrush which is a form of yeast. Anyhow sorry i wasnt much help.
Posted 3/13/2010 5:10 PM (GMT 0)
Thats why you should always take your probiotics when you are on antibiotics. They should be taken at least two hours difference from your antibiotics. Good luck!
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